PRAS40*

Leave a reply

Protein PRAS40* map

Identifiers
AKT1 substrate 1 (proline-rich)
HUGO:AKT1S1 HGNC:28426 ENTREZ:84335 UNIPROT:Q96B36 GENECARDS:AKT1S1 REACTOME:200146 KEGG:84335 ATLASONC:GC_AKT1S1 WIKI:AKT1S1

Maps_Modules
 Apoptosis  map  / AKT_MTOR  map
 Survival  map  / PI3K_AKT_MTOR  map

References
synonym:PRAS
PMID:18372248
PMID:17604271

PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome

References
s_akt1_re58( Survival  map ):
PMID:19446321
ANNOTATION:complex formation with DEPTOR antagonize/inhibits MTOR kinase activity
PMID:19706736
s_akt1_re61:( Survival  map ) PMID:17604271

Modifications:
In compartment: Cytoplasm
  1. PRAS40*@Cytoplasm map

In compartment: Membrane Lysosome

  1. PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map

Participates in complexes:
In compartment: Cytoplasm

  1. 14-3-3*|​unk:​PRAS40*|​pho@Cytoplasm map

  2. MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map
  3. MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map

In compartment: Membrane Lysosome

  1. 14-3-3*:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map

  2. MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  3. MLST8:​MTOR|​S2448_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  4. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  5. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  6. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  7. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  8. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map

Participates in reactions:
As Reactant or Product:

  1. MLST8:​MTOR:​RPTOR@Cytoplasm map + PRAS40*@Cytoplasm map → map MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map

  2. MLST8:​MTOR:​PRAS40*:​RPTOR@Cytoplasm map → map MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map
  3. 14-3-3*|​unk@Cytoplasm map + MLST8:​MTOR:​PRAS40*|​pho:​RPTOR@Cytoplasm map → map MLST8:​MTOR:​RPTOR@Cytoplasm map + 14-3-3*|​unk:​PRAS40*|​pho@Cytoplasm map
  4. PRAS40*@Cytoplasm map + MLST8@Cytoplasm map + RPTOR@Cytoplasm map + MTOR|​S2448_pho@Cytoplasm map → map MLST8:​MTOR|​S2448_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  5. PRAS40*@Cytoplasm map + MLST8@Cytoplasm map + RPTOR@Cytoplasm map + MTOR@Cytoplasm map + RAC1@Cytoplasm map → map s_s_akt1_s873
  6. 14-3-3*:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map → map s_s_akt1_s595
  7. s_s_akt1_s873 → map MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  8. MLST8:​MTOR|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  9. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map
  10. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  11. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  12. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
  13. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map
  14. PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map + 14-3-3*@Cytoplasm map → map 14-3-3*:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map

As Catalyser:

  1. MLST8:​MTOR|​S1261_pho|​S2448_emp:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map

  2. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*:​RAC1:​RPTOR@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S863_pho|​S877_pho@Membrane Lysosome map
  3. MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_emp|​T246_emp:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​S2448_emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map

Leave a Reply