PPP3CB_sub_trunc_endsub_*:PPP3R*

Complex PPP3CB_sub_trunc_endsub_*:PPP3R* map


Complex composition:

  1. PPP3CB_sub_trunc_endsub_* map
  2. PPP3R* map




(PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm

Identifiers
NAME:PPP3CB_sub_trunc_endsub_*:PPP3R*

Maps_Modules
 Survival  map  / WNT_NON_CANONICAL  map

References
Constitutively active
PMID:17662023, PMID:17593948, PMID:14627704
s_wnc2_re9( Survival  map ):
Calcineurin can be proteolysed which results in a truncated form of the catalytic subunit A. The truncated form is constitutively active and irreversible and does not require calcium and calmodulin for activation.
PMID:17593948, PMID:14627704
s_wnc2_re26:( Survival  map ) PMID:15036616, PMID:14741051
s_wnc2_re66:( Survival  map ) PMID:11796223
s_wnc2_re77:( Survival  map ) PMID:16648474

Confidence
REF=5 FUNC=0


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. (PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. (PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map + FOXO1|​pho|​emp|​pho@Cytoplasm map map (FOXO1|​pho|​emp|​pho:​PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map

  2. (PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map + NFAT*|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho@Cytoplasm map map (NFAT*|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho|​pho:​PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map
  3. s_s_wnc2_s333 map (PPP3CB_sub_trunc_endsub_*:​PPP3R*)|​active@Cytoplasm map

As Catalyser:

  1. s_s_wnc2_s86 map s_s_wnc2_s77

  2. FOXO1|​pho|​pho|​pho@Cytoplasm map map FOXO1|​pho|​emp|​pho@Cytoplasm map
  3. MEF2*|​pho|​pho|​pho|​pho|​pho|​pho@Cytoplasm map map MEF2*@Cytoplasm map
  4. ASK1*|​pho@Cytoplasm map map ASK1*@Cytoplasm map

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