PLC-_beta_*

Protein PLC-_beta_* map

Identifiers
phospholipase C, beta 1 (phosphoinositide-specific)
HUGO:PLCB1 HGNC:15917 ENTREZ:23236 UNIPROT:Q9NQ66 GENECARDS:PLCB1 REACTOME:61694 KEGG:23236 ATLASONC:PLCB1ID41742ch20p12 WIKI:PLCB1
phospholipase C, beta 2 (phosphoinositide-specific)
HUGO:PLCB2 HGNC:9055 ENTREZ:5330 UNIPROT:Q00722 GENECARDS:PLCB2 REACTOME:61696 ATLASONC:PLCB2ID41743ch15q15 WIKI:PLCB2
phospholipase C, beta 3 (phosphoinositide-specific)
HUGO:PLCB3 HGNC:9056 ENTREZ:5331 UNIPROT:Q01970 GENECARDS:PLCB3 REACTOME:61748 ATLASONC:GC_PLCB3 WIKI:PLCB3
phospholipase C, beta 4 (phosphoinositide-specific)
HUGO:PLCB4 HGNC:9059 ENTREZ:5332 UNIPROT:Q15147 GENECARDS:PLCB4 REACTOME:61698 KEGG:5332 ATLASONC:GC_PLCB4 WIKI:PLCB4

Maps_Modules
 Survival  map  / WNT_NON_CANONICAL  map

PLC-_beta_*@Cytoplasm

References
s_wnc1_re22( Survival  map ):
Only the Galpha_q subunit can activate PLC-beta
PMID:11395409
PMID:19359428
s_wnc1_re57( Survival  map ):
PLC-beta_2 and 3 are activated by the beta-and gamma subunit of the G-protein class q
PMID:20553968
s_wnc1_re58( Survival  map ):
PMID:16402909
PMID:12657629


Modifications:
In compartment: Cytoplasm
  1. PLC-_beta_*@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. G_alpha__sub_13q_endsub_*:​PLC-_beta_*:​_beta_-Arrestin*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. G_alpha__sub_13q_endsub_*:​_beta_-Arrestin*@Cytoplasm map + PLC-_beta_*@Cytoplasm map map G_alpha__sub_13q_endsub_*:​PLC-_beta_*:​_beta_-Arrestin*@Cytoplasm map

  2. G_beta_*:​G_gamma_*@Cytoplasm map + PLC-_beta_*@Cytoplasm map map s_s_wnc1_s278
  3. GTP:​RAC1@Cytoplasm map + PLC-_beta_*@Cytoplasm map map s_s_wnc1_s288

As Catalyser:

  1. PI4,5-P2@Cytoplasm map map DAG@Cytoplasm map + IP3@Cytoplasm map

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