PCAF*

Protein PCAF* map

Identifiers
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
“TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD”
HUGO:TAF5L HGNC:17304 ENTREZ:27097 UNIPROT:O75529 GENECARDS:TAF5L KEGG:27097 WIKI:TAF5L
K(lysine) acetyltransferase 2B
HUGO:KAT2B HGNC:8638 ENTREZ:8850 UNIPROT:Q92831 GENECARDS:KAT2B REACTOME:61366 KEGG:8850 ATLASONC:GC_KAT2B WIKI:KAT2B
K(lysine) acetyltransferase 2A
HUGO:KAT2A HGNC:4201 ENTREZ:2648 UNIPROT:Q92830 GENECARDS:KAT2A REACTOME:412498 KEGG:2648 ATLASONC:GC_KAT2A WIKI:KAT2A
KAT3B, E1A binding protein p300
HUGO:EP300 HGNC:3373 ENTREZ:2033 UNIPROT:Q09472 GENECARDS:EP300 REACTOME:61164 KEGG:2033 ATLASONC:P300ID97 WIKI:EP300
“p300/CBP-associated factor” PCAF

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 Apoptosis  map  / APOPTOSIS_GENES  map
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / G2_M_CHECKPOINT  map
 Cell cycle  map  / E2F1  map
 Survival  map  / WNT_CANONICAL  map

References
PMID:11804596, PMID:19407812, PMID:12660246
In reality, many kinds of histone acetyltransferases: p300 (EP300) + CBP (CREBBP) + PCAF + GCN5(GCN5L2), or the Tip60 complex: Tip60(HTATIP) + TRRAP + p400(EP400) + Tip48(RUVBL2) + Tip49(RUVBL1)
PMID:15121871

PCAF*@default

References
d_re34:( DNA repair  map ) PMID:19788416
d_re404( DNA repair  map ):
Acetylation of c-Myc keeps it inactive and prevents G1/S propagation
PMID:15522869


Modifications:
In compartment: Nucleus
  1. PCAF*@Nucleus map

In compartment: default

  1. PCAF*@default map

Participates in complexes:
In compartment: Nucleus

  1. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map

  2. DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. DP1*:​E2F1|​Lys_ace@Nucleus map + PCAF*@Nucleus map map DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map

  2. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map PCAF*@Nucleus map + DP1*:​E2F1|​Lys_ace|​Ser364_pho@Nucleus map
  3. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map DP1*:​E2F1|​Lys_ace|​Ser31_pho@Nucleus map + PCAF*@Nucleus map
  4. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map
  5. DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map map PCAF*@Nucleus map + E2F1|​pho|​Lys_ace@Nucleus map + DP1*|​pho@Nucleus map

As Catalyser:

  1. PPARGC1A@Nucleus map map PPARGC1A|​ace@Nucleus map

  2. DP1*:​E2F1@Nucleus map map DP1*:​E2F1|​Lys_ace@Nucleus map
  3. p53*@default map map p53*|​pho|​ace|​active@default map
  4. MYC@default map map MYC|​ace@default map
  5. p73*@default map map p73*|​Y99_pho|​ace|​active@default map
  6. _beta_-Catenin*@Nucleus map map _beta_-Catenin*|​ace@Nucleus map

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