p107*

Protein p107* map

Identifiers
retinoblastoma-like 1 (p107)
HUGO:RBL1 HGNC:9893 ENTREZ:5933 UNIPROT:P28749 GENECARDS:RBL1 REACTOME:62848 KEGG:5933 ATLASONC:GC_RBL1 WIKI:RBL1

Maps_Modules
 DNA repair  map  / G1_S_CHECKPOINT  map
 DNA repair  map  / G1_CC_PHASE  map
 DNA repair  map  / S_CC_PHASE  map
 Cell cycle  map  / CYCLINA  map
 Cell cycle  map  / CYCLINE  map
 Cell cycle  map  / E2F4  map

References
PMID:18590585, PMID:17303408, PMID:17660363, PMID:7575488, PMID:15279786
More present in proliferating cells.
PMID:15838516
3 phosphorylation sites that are CDK-dependants (CYCLIND-CDK4/6): T369, S650, S964.
PMID:12006580
10 phosphorylation sites conserved in p130.
PMID:11157749

p107*@default

References
d_re405( DNA repair  map ):
p107 interacts with c-Myc and inhibits c-Myc activity and G1/S propagation:
PMID:8076603

p107*@Nucleus

References
c_re91:( Cell cycle  map ) PMID:15231644
c_re1273:( Cell cycle  map ) PMID:15456871, PMID:12006580, PMID:11237530


Modifications:
In compartment: Nucleus
  1. p107*@Nucleus map

  2. p107*|​pho@Nucleus map

In compartment: default

  1. p107*@default map

  2. p107*|​pho@default map

Participates in complexes:
In compartment: Nucleus

  1. DP2*:​E2F4:​p107*@Nucleus map

  2. CDK2:​CyclinA*:​p107*@Nucleus map
  3. DP2*:​E2F4:​p107*|​pho@Nucleus map
  4. CDK2|​Thr160_pho:​CyclinE*:​p107*@Nucleus map

In compartment: default

  1. MYC:​p107*@default map

  2. E2F4_5*:​p107*@default map
  3. E2F4_5*:​p107*|​pho@default map
  4. CDK2:​CyclinE*:​p107*@default map
  5. CDK2:​CyclinA1*:​p107*@default map

Participates in reactions:
As Reactant or Product:

  1. p107*@Nucleus map + CDK2:​CyclinA*@Nucleus map map CDK2:​CyclinA*:​p107*@Nucleus map

  2. CDK2|​Thr160_pho:​CyclinE*@Nucleus map + p107*@Nucleus map map CDK2|​Thr160_pho:​CyclinE*:​p107*@Nucleus map
  3. DP2*:​E2F4@Nucleus map + p107*@Nucleus map map DP2*:​E2F4:​p107*@Nucleus map
  4. DP2*:​E2F4:​p107*@Nucleus map map DP2*:​E2F4:​p107*|​pho@Nucleus map
  5. DP2*:​E2F4:​p107*|​pho@Nucleus map map p107*|​pho@Nucleus map + DP2*@Nucleus map + E2F4@Nucleus map
  6. E2F4_5*@default map + p107*@default map map E2F4_5*:​p107*@default map
  7. E2F4_5*:​p107*@default map map E2F4_5*@default map + p107*@default map
  8. p107*@default map + CDK2:​CyclinE*@default map map CDK2:​CyclinE*:​p107*@default map
  9. p107*@default map + CDK2:​CyclinA1*@default map map CDK2:​CyclinA1*:​p107*@default map
  10. E2F4_5*:​p107*@default map map E2F4_5*:​p107*|​pho@default map
  11. E2F4_5*:​p107*|​pho@default map map p107*|​pho@default map + E2F4_5*@default map
  12. p107*|​pho@default map map degraded
  13. MYC@default map + p107*@default map map MYC:​p107*@default map

As Catalyser:

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