MYC

Gene MYC map

Identifiers
v-myc myelocytomatosis viral oncogene homolog
HUGO:MYC HGNC:7553 ENTREZ:4609 UNIPROT:P01106 GENECARDS:MYC REACTOME:59773 KEGG:4609 ATLASONC:MYCID27 WIKI:MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
“v-myc avian myelocytomatosis viral oncogene homolog”

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 Apoptosis  map  / APOPTOSIS_GENES  map
 Survival  map  / MAPK  map
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

gMYC@Nucleus

References
e_re1123( EMT  map ):
PMID:15810077
Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis.
PMID:22943793
Role of TGFB in regulation of cell cycle:
Physiologically, TGFB is a potent inhibitor of cell cycle.
It induces expression of p15INK4B and represses expression of c-Myc
Low levels of c-Myc allows TGFB to induce p15INK4B and p21CIP1 transcription

gMYC@Gene compartment

References
c_re965:( Cell cycle  map ) PMID:11564866, PMID:90001421
c_re994:( Cell cycle  map ) PMID:12150994
c_re1009:( Cell cycle  map ) PMID:12004135
c_re1141:( Cell cycle  map ) PMID:11564866, PMID:12150994


Modifications:
In compartment: Gene compartment
  1. gMYC@Gene compartment map

In compartment: Nucleus

  1. gMYC@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. gMYC@Nucleus map map rMYC@Nucleus map

    2. E2F6@Nucleus map map gMYC@Gene compartment map
    3. E2F2_alone@Cytoplasm map map gMYC@Gene compartment map
    4. E2F3_alone@Cytoplasm map map gMYC@Gene compartment map
    5. E2F4@Nucleus map map gMYC@Gene compartment map
    6. E2F1_alone@Cytoplasm map map gMYC@Gene compartment map
    7. E2F5@Nucleus map map gMYC@Gene compartment map
    8. gMYC@Nucleus map map rMYC@Nucleus map
    9. gMYC@Nucleus map map MYC@Nucleus map
    10. MSK*|​pho@Nucleus map map gMYC@Nucleus map
    11. gMYC@Nucleus map map rMYC@Nucleus map
    12. gMYC@Nucleus map map rMYC@Nucleus map

    As Catalyser:

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