MYC

RNA MYC map

Identifiers
v-myc myelocytomatosis viral oncogene homolog
HUGO:MYC HGNC:7553 ENTREZ:4609 UNIPROT:P01106 GENECARDS:MYC REACTOME:59773 KEGG:4609 ATLASONC:MYCID27 WIKI:MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
“v-myc avian myelocytomatosis viral oncogene homolog”

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 Apoptosis  map  / APOPTOSIS_GENES  map
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

rMYC@Nucleus

References
e_re1123( EMT  map ):
PMID:15810077
Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis.
PMID:22943793
Role of TGFB in regulation of cell cycle:
Physiologically, TGFB is a potent inhibitor of cell cycle.
It induces expression of p15INK4B and represses expression of c-Myc
Low levels of c-Myc allows TGFB to induce p15INK4B and p21CIP1 transcription


Modifications:
In compartment: Nucleus
  1. rMYC@Nucleus map

Participates in complexes:
In compartment: Cytoplasm

  1. MIR34*:​MYC@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. gMYC@Nucleus map map rMYC@Nucleus map

  2. rMYC@Nucleus map map MYC@Nucleus map
  3. gMYC@Nucleus map map rMYC@Nucleus map
  4. rMYC@Nucleus map map MYC@Nucleus map
  5. gMYC@Nucleus map map rMYC@Nucleus map
  6. gMYC@Nucleus map map rMYC@Nucleus map

As Catalyser:

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