MP1*

Protein MP1* map

Identifiers
late endosomal/lysosomal adaptor MODULE:MAPK map and MTOR activator 3
MAP2K1IP1 “MODULE:MAPK map scaffold protein 1″ MAPKSP1 “mitogen-activated protein kinase kinase 1 interacting protein 1″
HUGO:LAMTOR3 HGNC:15606 ENTREZ:8649 UNIPROT:Q9UHA4 GENECARDS:LAMTOR3 KEGG:8649 ATLASONC:GC_LAMTOR3 WIKI:LAMTOR3

Maps_Modules
 Survival  map  / MAPK  map

References
MP1 is localised in late endosomes by P14 forming a very stable heterodimeric complex that is required for ERK activation.
It is required for efficient and sustained EGF-induced MEK and ERK activation (in late endosomes)
PMID:17178906

MP1*@Cytoplasm

References
s_mpk1_re17( Survival  map ):
MP1 is localised on late endosomes by P14.
PMID:17178906


Modifications:
In compartment: Cytoplasm
  1. MP1*@Cytoplasm map

Participates in complexes:
In compartment: Late Endosomes

  1. LAMTOR2:​MP1*@Late Endosomes map

  2. LAMTOR2:​MEK*:​MP1*@Late Endosomes map
  3. GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map
  4. GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map
  5. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map

Participates in reactions:
As Reactant or Product:

  1. LAMTOR2@Late Endosomes map + MP1*@Cytoplasm map map LAMTOR2:​MP1*@Late Endosomes map

  2. MEK*@Cytoplasm map + LAMTOR2:​MP1*@Late Endosomes map map LAMTOR2:​MEK*:​MP1*@Late Endosomes map
  3. GRB2:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map + LAMTOR2:​MEK*:​MP1*@Late Endosomes map map GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map
  4. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map map GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map + ERK*@Cytoplasm map + RAF1@Cytoplasm map
  5. RAF1@Cytoplasm map + GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map map GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map
  6. ERK*@Cytoplasm map + GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map map ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map
  7. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map map GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes map + ERK*|​pho|​pho@Cytoplasm map

As Catalyser:

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