MOMP

Phenotype MOMP map
MOMP@Mitochondrial outer membrane

References
mitochondrial outer membrane permeabilization
a_re8( Apoptosis  map ):
in Ba/F3 cells, stable expression of the C-terminal cleavage product of BECN1 sensitizes cells to IL3-deprivation induced apoptosis
in vitro, incubation of isolated mitochondria with recombinant BECN1 C-terminal cleavage product triggers release of Omi/HtrA2 and cytochrome c
PMID:11832478
in vitro CASP2 unlike CASP8 induce release of CYCS , DIABLO and AIF form purified mitochondria from Hela cells
a_re1:( Apoptosis  map ) hierarchical:post-MOMP
a_re2( Apoptosis  map ):
hierarchical:post-MOMP
PMID:14532003
PMID:10929711
PMID:12660240
in Hela upn taxol treatment
a_re3( Apoptosis  map ):
PMID:11803371
a_re4( Apoptosis  map ):
PMID:8879205
release of AIF is blocked by BCL2 overexpression
but data supporting direct involvment of MOMP not found in the literature
a_re5( Apoptosis  map ):
PMID:9892620
PMID:10318956
PMID:12611882
a_re6( Apoptosis  map ):
PMID:9508780
a_re9( Apoptosis  map ):
PMID:9894606
in Jurkat
a_re670:( Apoptosis  map ) PMID:15029247
a_re1225:( Apoptosis  map ) PMID:11452314

MOMP@Mitochondria

Maps_Modules
 Survival  map  / WNT_NON_CANONICAL  map

References
MOMP=mitochondrial outer membrane permeabilisation.
PMID:20709625
s_wnc2_re17:( Survival  map ) PMID:21738214


Modifications:
In compartment: Mitochondria
  1. MOMP@Mitochondria map

In compartment: Mitochondrial outer membrane

  1. MOMP@Mitochondrial outer membrane map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. Mitochondria outer~membrane integrity@Mitochondrial outer membrane map map MOMP@Mitochondrial outer membrane map

    2. s_s_wnc2_s54 map MOMP@Mitochondria map
    3. MOMP@Mitochondria map map Apoptosis@Mitochondria map
    4. MOMP@Mitochondria map map Necroptosis@Mitochondria map
    5. BAD|​pho|​pho@Mitochondria map map MOMP@Mitochondria map

    As Catalyser:

    1. Cytochrome_C*|​ferroheme@Mitochondrial intermembrane space map map Cytochrome_C*|​ferroheme@Cytoplasm map

    2. ENDOG@Mitochondrial intermembrane space map map ENDOG@Cytoplasm map
    3. DIABLO@Mitochondrial intermembrane space map map DIABLO@Cytoplasm map
    4. HTRA2@Mitochondrial intermembrane space map map HTRA2@Cytoplasm map
    5. cleaved~AIFM1*@Mitochondrial intermembrane space map map cleaved~AIFM1*@Cytoplasm map
    6. Caspase9*@Mitochondrial intermembrane space map map Caspase9*@Cytoplasm map
    7. Caspase3_cl_uncl*@Mitochondrial intermembrane space map map Caspase3_cl_uncl*@Cytoplasm map
    8. SEPT4@Mitochondrial intermembrane space map map SEPT4@Cytoplasm map
    9. Caspase2*@Mitochondrial intermembrane space map map Caspase2*@Cytoplasm map
    10. AK2@Mitochondrial intermembrane space map map AK2@Cytoplasm map

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