Gene Mismatched_nucleotide*

Identifiers
DNA with mismatched nucleotide incorporation
Node_Type:Generic

Maps_Modules
 DNA repair   / MMR 

References
PMID:23892398
PMID:22258607, PMID:22918414, PMID:20478261
PMID:22976800, PMID:22475811, PMID:22237395

gMismatched_nucleotide*@Nucleus

References
d_re528:( DNA repair  ) PMID:22237395
d_re26( DNA repair  ):
BER and MMR interaction and G2/M arrest in responce to o6-meG formation:
PMID:14614141
cMyc physically stimulates MSH2 and MLH1 and activates MMR:
PMID:15814658, PMID:12584560
d_re179:( DNA repair  ) reactionType:is.a

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Modifications:
In compartment: Nucleus

1. gMismatched_nucleotide*@Nucleus

Participates in complexes:

Participates in reactions:
As Reactant or Product:

1. gMismatched_nucleotide*@Nucleus → gDamaged_DNA*@Nucleus

2. gMismatched_nucleotide*@Nucleus → gMMR_DNA_st2*@Nucleus
3. gIntact_DNA*@Nucleus → gMismatched_nucleotide*@Nucleus
4. gMismatched_nucleotide*@Nucleus → gSingle_strand_breaks_SSB*@Nucleus
5. Replication error@Nucleus → gMismatched_nucleotide*@Nucleus

As Catalyser:

1. MLH1@default + MBD4@default → MBD4:​MLH1@default