Protein MKNK2 
Identifiers
MAP kinase interacting serine/threonine kinase 2
HUGO:MKNK2 HGNC:7111 ENTREZ:2872 UNIPROT:Q9HBH9 GENECARDS:MKNK2 KEGG:2872 ATLASONC:GC_MKNK2 WIKI:MKNK2
Maps_Modules
EMT / EMT_REGULATORS
References
PMID:9155017
Mnk1 and Mnk2 bind to Erk1, Erk2 and p38 but not JNK
Mnk1 and Mnk2 are in vitro substrates of Erk2 and p38
Mnk1 is a MAP kinase-activated eIF-4E kinase
MKNK2@Cytoplasm
References
e_re397( EMT ):
PMID:9604935
Phosphorylation of ERK-1/2 promotes its homodimerization
PMID:18775330
Scaffolds and ERK dimers are essential for the activation of cytoplasmic but not nuclear substrates.
Dimerization is critical for connecting the scaffolded ERK complex to cognate cytoplasmic substrates.
Contrarily, nuclear substrates associate to ERK monomers.
PMID:9155017
Mnk1 and Mnk2 bind to Erk1, Erk2 and p38 but not JNK
Mnk1 and Mnk2 are in vitro substrates of Erk2 and p38
Mnk1 is a MAP kinase-activated eIF-4E kinase
MKNK2|pho@Cytoplasm
References
e_re397( EMT ):
PMID:9604935
Phosphorylation of ERK-1/2 promotes its homodimerization
PMID:18775330
Scaffolds and ERK dimers are essential for the activation of cytoplasmic but not nuclear substrates.
Dimerization is critical for connecting the scaffolded ERK complex to cognate cytoplasmic substrates.
Contrarily, nuclear substrates associate to ERK monomers.
PMID:9155017
Mnk1 and Mnk2 bind to Erk1, Erk2 and p38 but not JNK
Mnk1 and Mnk2 are in vitro substrates of Erk2 and p38
Mnk1 is a MAP kinase-activated eIF-4E kinase
Modifications:
In compartment: Cytoplasm
- MKNK2@Cytoplasm
- MKNK2|pho@Cytoplasm
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser: