MIR200A:_beta_-Catenin*_ZEB1_ZEB2*

Complex MIR200A:_beta_-Catenin*_ZEB1_ZEB2* map


Complex composition:

  1. MIR200A map
  2. _beta_-Catenin*_ZEB1_ZEB2* map




MIR200A:​_beta_-Catenin*_ZEB1_ZEB2*@Cytoplasm

Identifiers
NAME:MIR200A:_beta_-Catenin*_ZEB1_ZEB2*

Maps_Modules
 EMT  map  / EMT_REGULATORS  map

References
PMID:19931509
miR-200a downregulates ZEB2 and CTNNB1
This downregulation inhibits carcinoma cell growth, migration and invasion.
e_re1117( EMT  map ):
PMID:19703993
Upregulation of miR-200a decreased the expression of ZEB1 and ZEB2, with consequent increased expression of E-cadherin,
Downregulation of miR-200a in meningiomas and arachnoidal cells resulted in increased expression of beta-catenin and cyclin D1 involved in cell proliferation
PMID:20592490
PMID:22211245
CTNNB1 is direct target of MIR200A

Confidence
REF=3 FUNC=4


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. MIR200A:​_beta_-Catenin*_ZEB1_ZEB2*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. r_beta_-Catenin*_ZEB1_ZEB2*@Nucleus map + arMIR200A@Nucleus map map MIR200A:​_beta_-Catenin*_ZEB1_ZEB2*@Cytoplasm map

As Catalyser:

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