MIR200*

Antisense RNA MIR200* map

Identifiers
microRNA 200a
HUGO:MIR200A HGNC:31578 ENTREZ:406983 GENECARDS:MIR200A KEGG:406983 ATLASONC:GC_MIR200A WIKI:MIR200A
microRNA 200b
HUGO:MIR200B HGNC:31579 ENTREZ:406984 GENECARDS:MIR200B KEGG:406984 ATLASONC:GC_MIR200B WIKI:MIR200B
microRNA 200c
HUGO:MIR200C HGNC:31580 ENTREZ:406985 GENECARDS:MIR200C KEGG:406985 ATLASONC:MIR200CID51054ch12p13 WIKI:MIR200C
microRNA 141
HUGO:MIR141 HGNC:31528 ENTREZ:406933 GENECARDS:MIR141 KEGG:406933 ATLASONC:GC_MIR141 WIKI:MIR141
microRNA 429
HUGO:MIR429 HGNC:13784 ENTREZ:554210 GENECARDS:MIR429 KEGG:554210 ATLASONC:GC_MIR429 WIKI:MIR429

Maps_Modules
 EMT  map  / EMT_REGULATORS  map

References
PMID:21336307
PMID:22370643
Regulation of BMI1 and JAG1
PMID:21224848
Feedback loops
PMID:225147423

arMIR200*@Nucleus

References
e_re356( EMT  map ):
PMID:22945800
PMID:22286765
Six1 induces ZEB1 and EMT through transcriptional repression of miR200.
PMID:20706219
Feedback loop between ZEB1, ZEB2 and MIR200 family
PMID:19935649
ZEB1 inhibits expression of MIR200 family
PMID:22514743
SNAI1 represses expression of all MIR200 family members.
e_re1115( EMT  map ):
PMID:22311119
miR-200b regulates ZEB2 expression and thus controls metastasis in gastric cancer
e_re1118( EMT  map ):
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.


Modifications:
In compartment: Nucleus
  1. arMIR200*@Nucleus map

Participates in complexes:
In compartment: Cytoplasm

  1. JAG1:​MIR200*@Cytoplasm map

  2. MIR200*:​SNAI2@Cytoplasm map
  3. MIR200*:​ZEB1_ZEB2*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. arMIR200*@Nucleus map + rZEB1_ZEB2*@Nucleus map map MIR200*:​ZEB1_ZEB2*@Cytoplasm map

  2. arMIR200*@Nucleus map map arMIR200A@Nucleus map
  3. arMIR200*@Nucleus map map arMIR200B@Nucleus map
  4. arMIR200*@Nucleus map map arMIR200C@Nucleus map
  5. arMIR200*@Nucleus map map arMIR141@Nucleus map
  6. arMIR200*@Nucleus map map arMIR429@Nucleus map
  7. gMIR200*@Nucleus map map arMIR200*@Nucleus map

As Catalyser:

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