MDM2

RNA MDM2 map

Identifiers
Mdm2 p53 binding protein homolog (mouse)
HUGO:MDM2 HGNC:6973 ENTREZ:4193 UNIPROT:Q00987 GENECARDS:MDM2 REACTOME:95018 KEGG:4193 ATLASONC:MDM2ID115ch12q15 WIKI:MDM2
Mdm2 p53 binding protein homo

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 Survival  map  / PI3K_AKT_MTOR  map

References
MDM2 = ubiquitin-ligase, regulates p53 stability: induce its degradation via the proteasome.
PMID:15024084
PMID:20068088
PMID:20673124

rMDM2@Nucleus

References
e_re1293( EMT  map ):
PMID:17550342
SNAI2 represses MDM2 expression, thus skip p53 from proteasomal degradation


Modifications:
In compartment: Nucleus
  1. rMDM2@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. gMDM2@Nucleus map map rMDM2@Nucleus map

    2. rMDM2@Nucleus map map MDM2@Nucleus map
    3. gMDM2@Nucleus map map rMDM2@Nucleus map

    As Catalyser:

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