MCF2

Protein MCF2 map

Identifiers
MCF.2 cell line derived transforming sequence
HUGO:MCF2 HGNC:6940 ENTREZ:4168 UNIPROT:P10911 GENECARDS:MCF2 REACTOME:402771 KEGG:4168 ATLASONC:GC_MCF2 WIKI:MCF2

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CYTOSKELETON_POLARITY  map

References
PMID:11394904
PMID:10652228
GEF activity of MCF2 (DBL) towards CDC42 or Rac1 is enhanced upon TNK2 (ACK1) phosphorylation.

MCF2@Cytoplasm

References
e_re838( EMT  map ):
PMID:11394904
PMID:10652228
GEF activity of MCF2 (DBL) towards CDC42 or Rac1 is enhanced upon TNK2 (ACK1) phosphorylation.

MCF2|​pho|​active@Cytoplasm

References
e_re828( EMT  map ):
PMID:11394904
PMID:10652228
GEF activity of MCF2 (DBL) towards CDC42 or Rac1 is enhanced upon TNK2 (ACK1) phosphorylation.
e_re891( EMT  map ):
PMID:8836113
GEFs are essential for CDC42 activation. They promote the exchange of GDP to GTP to generate the activated form of CDC42 capable of recognizing downstram targets.
PMID:10843989
MCF2 (DBL) as a GEF of CDC42


Modifications:
In compartment: Cytoplasm
  1. MCF2@Cytoplasm map

  2. MCF2|​pho|​active@Cytoplasm map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. Rac1_GEFs*@Cytoplasm map map MCF2|​pho|​active@Cytoplasm map

    2. MCF2@Cytoplasm map map MCF2|​pho|​active@Cytoplasm map
    3. CDC42_GEFs*@Cytoplasm map map MCF2|​pho|​active@Cytoplasm map

    As Catalyser:

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