Identifiers
mitogen-activated protein kinase-activated protein kinase 2
HUGO:MAPKAPK2 HGNC:6887 ENTREZ:9261 UNIPROT:P49137 GENECARDS:MAPKAPK2 REACTOME:59309 KEGG:9261 ATLASONC:MAPKAPK2ID41295ch1q32 WIKI:MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 3
HUGO:MAPKAPK3 HGNC:6888 ENTREZ:7867 UNIPROT:Q16644 GENECARDS:MAPKAPK3 REACTOME:187732 KEGG:7867 ATLASONC:GC_MAPKAPK3 WIKI:MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 5
HUGO:MAPKAPK5 HGNC:6889 ENTREZ:8550 UNIPROT:Q8IW41 GENECARDS:MAPKAPK5 KEGG:8550 ATLASONC:GC_MAPKAPK5 WIKI:MAPKAPK5
References
MAPKAPK2 (MK2) MAPKAPK3 (MK3) and MAPKAPK5 (PRAK) are phosphorylated and activated by P38alpha and P38 beta. They catalyse phosphorylation of HSP27.
PMID:11274345
MAPKAPK*@Cytoplasm
References
s_mpk1_re163( Survival ):
MAPKAPK2 and MAPKAPK3 are phosphorylated and activated by P38alpha and P38 beta.
PMID:11274345
MAPKAPK*|pho@Cytoplasm
References
s_mpk1_re163( Survival ):
MAPKAPK2 and MAPKAPK3 are phosphorylated and activated by P38alpha and P38 beta.
PMID:11274345
s_mpk1_re164( Survival ):
MAPKAPK2 MAPKAPK3 and PRAK catalyse phosphorylation of HSP27.
s_mpk1_re188( Survival ):
P38 is able to suppress RAS-dependent JNK activation (probably through PRAK and MK2).
PMID:10978313
s_s_mpk1_re164( Survival ):
Modifications:
In compartment: Cytoplasm
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser: