MAP3K10_11*

Protein MAP3K10_11* map

Identifiers
mitogen-activated protein kinase kinase kinase 10
MLK2
HUGO:MAP3K10 HGNC:6849 ENTREZ:4294 UNIPROT:Q02779 GENECARDS:MAP3K10 KEGG:4294 ATLASONC:GC_MAP3K10 WIKI:MAP3K10
mitogen-activated protein kinase kinase kinase 11
MLK3 PTK1
HUGO:MAP3K11 HGNC:6850 ENTREZ:4296 UNIPROT:Q16584 GENECARDS:MAP3K11 KEGG:4296 ATLASONC:GC_MAP3K11 WIKI:MAP3K11

Maps_Modules
 Survival  map  / MAPK  map

References
MLK3 and MLK2 two MAP3Ks of JNK pathway can interact with RAC1 in a GTP-dependent manner.
MLK3 has the potential to positively regulate the ERK / MAPK  map pathway by directly phosphorylating and activating MEK.
PMID:11274345 PMID:12738796

MAP3K10_11*@Cytoplasm

References
s_mpk1_re151( Survival  map ):
MLK3 and MLK2 two MAP3Ks of JNK pathway can interact with RAC1 in a GTP-dependent manner.
PMID:11274345


Modifications:
In compartment: Cytoplasm
  1. MAP3K10_11*@Cytoplasm map

Participates in complexes:
In compartment: Cytoplasm

  1. MAP3K10_11*|​pho:​RAC1|​pho:​RTK*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. GRB2:​RAC1|​pho:​RTK*:​SOS*@Plasma Membrane map + MAP3K10_11*@Cytoplasm map map MAP3K10_11*|​pho:​RAC1|​pho:​RTK*@Cytoplasm map

As Catalyser:

  1. MAP2K4@Cytoplasm map map MAP2K4|​pho|​pho@Cytoplasm map

  2. MAP2K7@Cytoplasm map map MAP2K7|​pho|​pho@Cytoplasm map
  3. MEK*@Cytoplasm map map MEK*|​pho|​pho@Cytoplasm map

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