LIG4

Protein LIG4 map

Identifiers
ligase IV, DNA, ATP-dependent
HUGO:LIG4 HGNC:6601 ENTREZ:3981 UNIPROT:P49917 GENECARDS:LIG4 REACTOME:53792 ATLASONC:GC_LIG4 WIKI:LIG4

Maps_Modules
 DNA repair  map  / C_NHEJ  map

References
PMID:20691907, PMID:12471202, PMID:19772495, PMID:19346677, PMID:15703371, PMID:19847258, PMID:16697054, PMID:19473888, PMID:19808869


Modifications:
In compartment: default
  1. LIG4@default map

Participates in complexes:
In compartment: Nucleus

  1. APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map

In compartment: default

  1. LIG4:​PNK*:​XRCC4@default map

  2. LIG4:​XLF*:​XRCC4|​hm2@default map

Participates in reactions:
As Reactant or Product:

  1. XRCC4@default map + LIG4@default map + PNK*@default map map LIG4:​PNK*:​XRCC4@default map

  2. Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho|​active@default map + LIG4:​XLF*:​XRCC4|​hm2@default map + PARP3@Nucleus map + DNA-PK*|​hm2|​active@default map + Ku80*@default map + Ku70*@Nucleus map + APLF@Nucleus map map APLF:​Artemis*|​S645_pho|​S385_pho|​S516_pho|​S518_pho:​DNA-PK*|​hm2:​Ku70*:​Ku80*:​LIG4:​PARP3:​XLF*:​XRCC4|​hm2@Nucleus map
  3. XRCC4|​hm2@default map + LIG4@default map + XLF*@default map map LIG4:​XLF*:​XRCC4|​hm2@default map

As Catalyser:

  1. gC_NHEJ_DNA_st2*@Nucleus map map gC_NHEJ_DNA_st3*@Nucleus map

  2. gC_NHEJ_DNA_st4*@Nucleus map map gC_NHEJ_DNA_st5*@Nucleus map

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