Laminin1*

Protein Laminin1* map

Identifiers
Laminin 1*
laminin, alpha 1
HUGO:LAMA1 HGNC:6481 ENTREZ:284217 UNIPROT:P25391 GENECARDS:LAMA1 REACTOME:58609 KEGG:284217 ATLASONC:GC_LAMA1 WIKI:LAMA1
laminin, beta 1
CLM, “cutis laxa with marfanoid phenotype”
HUGO:LAMB1 HGNC:6486 ENTREZ:3912 UNIPROT:P07942 GENECARDS:LAMB1 REACTOME:58619 KEGG:3912 ATLASONC:GC_LAMB1 WIKI:LAMB1
laminin, gamma 1
HUGO:LAMC1 HGNC:6492 ENTREZ:3915 UNIPROT:P11047 GENECARDS:LAMC1 REACTOME:58631 KEGG:3915 ATLASONC:GC_LAMC1 WIKI:LAMC1

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / CELL_MATRIX_ADHESIONS  map
 EMT  map  / ECM  map

References
PMID:114518
Laminin-1: LAMA1, LAMB1, LAMC1

Laminin1*@Extracellular space

References
e_re910( EMT  map ):
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
Integrins a1b1, a2b1, a10b1 and a11b1 bind to collagens
PMID:12297042
Cell adhesion to components of the ECM is important in the angiogenesis
PMID:2153105
PMID:2786007
PMID:7639691
PMID:10809728
integrins are receptors for different ECM proteins: Collagen 1, 4; Laminin 1, 8; Fibronectin and Vitronectin
PMID:7522194
PMID:16195317
Interactions between integrins and the ECM proteins result in focal cell adhesion and cytoskeleton remodeling.


Modifications:
In compartment: Extracellular space
  1. Laminin1*@Extracellular space map

Participates in complexes:
In compartment: Extracellular space

  1. Laminin1*:​a2b1*_a3b1*@Extracellular space map

  2. Laminin 1 partners*:​Laminin1*@Extracellular space map

Participates in reactions:
As Reactant or Product:

  1. Galectin 3 partners*@Extracellular space map map Laminin1*@Extracellular space map

  2. Laminin1*@Extracellular space map map Truncated Laminin1*@Extracellular space map
  3. Laminin1*@Extracellular space map + Laminin 1 partners*@Extracellular space map map Laminin 1 partners*:​Laminin1*@Extracellular space map
  4. Elastin partners*@Extracellular space map map Laminin1*@Extracellular space map
  5. Laminin 1 partners*:​Laminin1*@Extracellular space map map Cell-matrix adhesions@Extracellular space map
  6. a2b1*_a3b1*@Extracellular space map + Laminin1*@Extracellular space map map Laminin1*:​a2b1*_a3b1*@Extracellular space map
  7. LAMA1@Cytoplasm map + LAMB1@Cytoplasm map + LAMC1@Cytoplasm map map Laminin1*@Extracellular space map
  8. Laminin1*:​a2b1*_a3b1*@Extracellular space map map Cell-matrix adhesions@Extracellular space map

As Catalyser:

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