Ku70*:Ku80*:Securin*

Complex Ku70*:Ku80*:Securin* map


Complex composition:

  1. Ku80* map
  2. Ku70* map
  3. Securin* map




Ku70*:​Ku80*:​Securin*@default

Identifiers
NAME:Ku70*:Ku80*:Securin*

Maps_Modules
 DNA repair  map  / C_NHEJ  map

References
PMID:17962814
d_re374( DNA repair  map ):
Link between spindle checkpoint and ds break DNA repair pathway (C_NHEJ)
d_re80( DNA repair  map ):
The complex MRN:BRCA1:phos-Ub-CtIP is central in the shift toward HR, because it activates resection for HR and blocks Ku70/80 of C_NHEJ:
PMID:19357644, PMID:15485915, PMID:19490890, PMID:18716619 (for CDK-dep phosph), PMID:20051983

Confidence
REF=4 FUNC=5


Modifications:
Participates in complexes:
In compartment: default
  1. Ku70*:​Ku80*:​Securin*@default map

Participates in reactions:
As Reactant or Product:

  1. Ku70*:​Ku80*@Nucleus map + Securin*@default map map Ku70*:​Ku80*:​Securin*@default map

As Catalyser:

  1. gC_NHEJ_DNA_st1*@Nucleus map map gC_NHEJ_DNA_st2*@Nucleus map

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