ITGAL:ITGB2

Complex ITGAL:ITGB2 map


Complex composition:

  1. ITGB2 map
  2. ITGAL map




ITGAL:​ITGB2@Cytoplasm

Identifiers
NAME:ITGAL:ITGB2

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map
 EMT  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:21270398
The aLb2 integrin (so-called LFA-1) is important for the adhesion of T cells and NK (natural killer) cells to target cells.

Confidence
REF=1 FUNC=0

ITGAL:​ITGB2@Cytoplasm

Identifiers
NAME:ITGAL:ITGB2

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map
 EMT  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:21270398
The aLb2 integrin (so-called LFA-1) is important for the adhesion of T cells and NK (natural killer) cells to target cells.

Confidence
REF=1 FUNC=4


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. ITGAL:​ITGB2@Cytoplasm map

  2. ITGAL:​ITGB2@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Talin partners*@Cytoplasm map map ITGAL:​ITGB2@Cytoplasm map

  2. ITGAL@Cytoplasm map + ITGB2@Cytoplasm map map ITGAL:​ITGB2@Cytoplasm map
  3. ITGAL:​ITGB2@Cytoplasm map map ITGAL:​ITGB2@Cytoplasm map

As Catalyser:

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