IMP*:KSR1:MEK*

Complex IMP*:KSR1:MEK* map


Complex composition:

  1. KSR1 map
  2. MEK* map
  3. IMP* map




IMP*:​KSR1:​MEK*@Cytoplasm

Identifiers
NAME:IMP*:KSR1:MEK*

References
s_mpk1_re35( Survival  map ):
RasGTP interacts with IMP cleaving it from KSR1. In this way KSR1 can play its role of scaffolding protein for ERK cascade.
Ras activation causes the cleavage of 14-3-3 from KSR1 (not modelled) exposing the membrane-targeting C1 domain as well as the docking site for ERK1/2.
PMID:14724641 PMID:17496910

Confidence
REF=1 FUNC=4


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. IMP*:​KSR1:​MEK*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. IMP*:​KSR1:​MEK*@Cytoplasm map map IMP*@Cytoplasm map + KSR1:​MEK*@Cytoplasm map

As Catalyser:

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