IKK_beta_*

Protein IKK_beta_* map

Identifiers
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
HUGO:IKBKB HGNC:5960 ENTREZ:3551 UNIPROT:O14920 GENECARDS:IKBKB REACTOME:57216 KEGG:3551 ATLASONC:GC_IKBKB WIKI:IKBKB

Maps_Modules
 Apoptosis  map  / AKT_MTOR  map
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / CASPASES  map
 Apoptosis  map  / TNF_RESPONSE  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:20300203
PMID:17693255
PMID:18716620

IKK_beta_*@Cytoplasm

References
a_re308( Apoptosis  map ):
PMID:18408758
in human epithelial ovarian cancer cells
a_re355:( Apoptosis  map ) PMID:17693255
a_re411:( Apoptosis  map ) PMID:19818716
a_re648( Apoptosis  map ):
hierarchical:post-MOMP
reactionType:casp.cleavage
PMID:11741536
in MCF7 upon TNF
in Hela upon TNF + CHX
a_re1026( Apoptosis  map ):
PMID:15184672
in Jurkat, nitrosothiol mediated S-nitrosylation of IKKbeta Cys179 correlates with its inactivation

IKK_beta_*|​ubi@Cytoplasm

References
a_re411:( Apoptosis  map ) PMID:19818716

IKK_beta_*|​-SNO@Cytoplasm

References
a_re1026( Apoptosis  map ):
PMID:15184672
in Jurkat, nitrosothiol mediated S-nitrosylation of IKKbeta Cys179 correlates with its inactivation


Modifications:
In compartment: Cytoplasm
  1. IKK_beta_*@Cytoplasm map

  2. IKK_beta_*|​ubi@Cytoplasm map
  3. IKK_beta_*|​-SNO@Cytoplasm map

In compartment: Nucleus

  1. IKK_beta_*@Nucleus map

Participates in complexes:
In compartment: TNFRSF1 Receptor Complex

  1. CHUK:​IKBKG:​IKK_beta_*@TNFRSF1 Receptor Complex map

  2. CHUK:​IKBKG:​IKK_beta_*|​pho@TNFRSF1 Receptor Complex map

Participates in reactions:
As Reactant or Product:

  1. IKK_beta_*@Cytoplasm map + NO@Cytoplasm map map IKK_beta_*|​-SNO@Cytoplasm map

  2. IKK_beta_*@Cytoplasm map + CHUK@Cytoplasm map + IKBKG@TNFRSF1 Receptor Complex map map CHUK:​IKBKG:​IKK_beta_*@TNFRSF1 Receptor Complex map
  3. CHUK:​IKBKG:​IKK_beta_*@TNFRSF1 Receptor Complex map map CHUK:​IKBKG:​IKK_beta_*|​pho@TNFRSF1 Receptor Complex map
  4. rIKBKB@Nucleus map map IKK_beta_*@Cytoplasm map
  5. IKK_beta_*@Cytoplasm map map IKK_beta_*|​ubi@Cytoplasm map
  6. IKK_beta_*|​ubi@Cytoplasm map map degraded
  7. IKK_beta_*@Cytoplasm map map cleaved~IKBKB*@Cytoplasm map
  8. IKK_beta_*@Nucleus map map Chromosome integrity and DSB repair@Nucleus map
  9. rRAD51@Nucleus map map IKK_beta_*@Nucleus map

As Catalyser:

  1. NFKBIA@Cytoplasm map map NFKBIA|​pho@Cytoplasm map

  2. TSC1:​TSC2|​M1_unk@Cytoplasm map map TSC1|​S487_pho|​S511_pho:​TSC2|​M1_unk@Cytoplasm map
  3. TSC1@Endosome Membrane map map TSC1|​pho|​pho@Endosome Membrane map

Leave a Reply