Identifiers
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
Maps_Modules
EMT / EMT_REGULATORS
References
PMID:17490644
Snai1 and TCF3 (E47) upregulate both mRNA and protein level of ID1
This upregulation depends on SP1 or AP1 co-transcription factors
gID1@Nucleus
References
e_re1225( EMT ):
PMID:17490644
Snai1 and TCF3 (E47) upregulate both mRNA and protein level of ID1
This upregulation depends on SP1 or AP1 co-transcription factors
Erk contributes to the recruitment or assembly of proteins to Id-1 promoter
PMID:16831886
PMID:18832382
HMGA2 directly binds to the SNAIL1 promoter and acts as a transcriptional regulator of SNAIL1 expression.
HMGA2 cooperates with SMAD3 and SMAD4 to execute a dramatic super-induction of the SNAIL1 promoter.
Same results were obtained with SNAI2, ZEB1, ZEB2 and TWIST1
HMGA2 cooperates with TGFB1 signaling to represse ID2 transcriptomal expression
Modifications:
In compartment: Nucleus
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser: