HES1

Protein HES1 map

Identifiers
hairy and enhancer of split 1, (Drosophila)
HUGO:HES1 HGNC:5192 ENTREZ:3280 UNIPROT:Q14469 GENECARDS:HES1 REACTOME:56466 KEGG:3280 ATLASONC:GC_HES1 WIKI:HES1
“hairy homolog (Drosophila)” HRY

Maps_Modules
 DNA repair  map  / FANCONI  map
 DNA repair  map  / TLS  map
 Survival  map  / WNT_CANONICAL  map

References
PMID:8020957, PMID:12535671, PMID:12972610, PMID:18550849, PMID:20832754
FA core complex regulates REV1 and activated TLS
PMID:22266823

HES1@Nucleus

References
s_wca3_re37:( Survival  map ) PMID:15367661


Modifications:
In compartment: Nucleus
  1. HES1@Nucleus map

In compartment: default

  1. HES1@default map

Participates in complexes:
In compartment: Nucleus

  1. HES1:​TLE*|​S239_pho@Nucleus map

In compartment: default

  1. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map

  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

Participates in reactions:
As Reactant or Product:

  1. FANCA|​pho:​FANCG|​S7_pho@default map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map + FAAP24*:​FANCM@default map + FAAP100*:​FANCB:​FANCL@default map + BLM@Nucleus map + HES1@default map + FAAP20*@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map

  2. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map
  3. HES1:​TLE*|​S239_pho@Nucleus map map Notch pathway@Nucleus map
  4. HES1@Nucleus map + TLE*|​S239_pho@Nucleus map map HES1:​TLE*|​S239_pho@Nucleus map
  5. rHES1@Nucleus map map HES1@Nucleus map

As Catalyser:

  1. gFanconi_DNA_st2*@Nucleus map map gFanconi_DNA_st3*@Nucleus map

  2. FANCD2|​pho@default map map FANCD2|​K561_ubi|​pho@default map
  3. FANCI|​pho@default map map FANCI|​K523_ubi|​pho@default map
  4. gFanconi_DNA_st4*@Nucleus map map gFanconi_DNA_st5*@Nucleus map
  5. FANCD2@default map map FANCD2|​pho@default map
  6. FANCD2|​K561_ubi|​pho@default map + MRE11*:​NBS1*|​S343_pho:​RAD50@default map + ATR|​pho|​active@Nucleus map map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@default map
  7. gTLS_DNA_st1*@Nucleus map map gTLS_DNA_st2*@Nucleus map

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