Simple molecule GTP
GTP@Mitochondrial Matrix
Identifiers
CHEBI:15996 KEGGCOMPOUND:C00044 CAS:86-01-1
Maps_Modules
Apoptosis / MITOCH_METABOLISM
GTP@Cytoplasm
Identifiers
CHEBI:15996 KEGGCOMPOUND:C00044 CAS:86-01-1
Maps_Modules
Apoptosis / MITOCH_METABOLISM
References
a_re1094:( Apoptosis ) reactionType:is.a
GTP@Vaceolae
References
s_wca1_re25:( Survival ) PMID:21606194 PMID:19705439
Modifications:
In compartment: Cytoplasm
In compartment: Mitochondrial Matrix
In compartment: Vaceolae
Participates in complexes:
In compartment: Cytoplasm
- GTP:HRAS@Cytoplasm
- GTP:RAC1@Cytoplasm
- GTP:RHOA@Cytoplasm
- GTP:RHOB@Cytoplasm
- CDC42:GTP@Cytoplasm
- (GTP:G_alpha_*)|active@Cytoplasm
- CDC42:GTP:PAR6*@Cytoplasm
- GTP:G_alpha_*:PLC_beta_*@Cytoplasm
- GTP:RHOA:RhoA_cytoskeletal_effectors*@Cytoplasm
- GTP:RHOB:RhoB_cytoskeletal_effectors*@Cytoplasm
- DIA*|open:GTP:RHOA@Cytoplasm
- GTP:RHOA:ROCK*|open@Cytoplasm
- GTP:RAF1|S259_pho|S621_pho|S_pho|open:YWHAB@Cytoplasm
- GTP:HRAS:RAF1|S259_pho|S621_pho|S_pho|closed@Cytoplasm
In compartment: Vaceolae
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
Participates in reactions:
As Reactant or Product:
- GTP@Cytoplasm
→
purine ribonucleoside 5′-triphosphate@Cytoplasm
- GDP@Cytoplasm
+ ATP@Cytoplasm
→
GTP@Cytoplasm
+ ADP@Cytoplasm
- GTP@Cytoplasm
+ ATP@Cytoplasm
+ UTP@Cytoplasm
+ CTP@Cytoplasm
→
rRNA@Cytoplasm
- succinyl-CoA@Mitochondrial Matrix
+ GDP@Mitochondrial Matrix
→
succinate@Mitochondrial Matrix
+ coenzyme A@Mitochondrial Matrix
+ GTP@Mitochondrial Matrix
- RAC1@Cytoplasm
→
GTP:RAC1@Cytoplasm
- FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ WNT*@Extracellular space
+ LRP5_6*@Cytoplasm
→
FZD*:LRP5_6*:WNT*@Cytoplasm
+ (GTP:G_alpha_*)|active@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
- EDNRA:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ Endothelin1*@Extracellular space
→
EDNRA:Endothelin1*@Cytoplasm
+ G_beta_*:G_gamma_*@Cytoplasm
+ (GTP:G_alpha_*)|active@Cytoplasm
- (GTP:G_alpha_*)|active@Cytoplasm
+ PLC_beta_*@Cytoplasm
→
GTP:G_alpha_*:PLC_beta_*@Cytoplasm
- GDP:HRAS@Cytoplasm
→
GTP:HRAS@Cytoplasm
- RAF1|S259_pho|S621_pho|S_pho|closed:YWHAB@Cytoplasm
+ GTP:HRAS@Cytoplasm
→
GTP:HRAS:RAF1|S259_pho|S621_pho|S_pho|closed@Cytoplasm
+ YWHAB@Cytoplasm
- GTP:HRAS:RAF1|S259_pho|S621_pho|S_pho|closed@Cytoplasm
+ YWHAB@Cytoplasm
→
GTP:RAF1|S259_pho|S621_pho|S_pho|open:YWHAB@Cytoplasm
- GTP:RAF1|S259_pho|S621_pho|S_pho|open:YWHAB@Cytoplasm
+ ATP@Cytoplasm
→
RAF1|S259_pho|S621_pho|Y340_pho|Y341_pho|open@Cytoplasm
+ ADP@Cytoplasm
- GTP:RHOA@Cytoplasm
→
Tight junctions@Extracellular space
- GTP:RHOA@Cytoplasm
→
GDP:RHOA@Cytoplasm
- GDP:RHOA@Cytoplasm
→
GTP:RHOA@Cytoplasm
- GTP:RHOA@Cytoplasm
→
Establishment of cell polarity@Nucleus
- GTP:RHOA@Cytoplasm
→
Stress fiber formation@Nucleus
- ROCK*|closed@Nucleus
+ GTP:RHOA@Cytoplasm
→
GTP:RHOA:ROCK*|open@Cytoplasm
- GTP:RHOA@Cytoplasm
+ DIA*|closed@Cytoplasm
→
DIA*|open:GTP:RHOA@Cytoplasm
- GTP:RHOB@Cytoplasm
→
GDP:RHOB@Cytoplasm
- GDP:RHOB@Cytoplasm
→
GTP:RHOB@Cytoplasm
- GTP:RHOA:RhoA_cytoskeletal_effectors*@Cytoplasm
→
Cytoskeleton remodeling@Nucleus
- GTP:RHOB:RhoB_cytoskeletal_effectors*@Cytoplasm
→
Cytoskeleton remodeling@Nucleus
- GTP:RHOA@Cytoplasm
+ RhoA_cytoskeletal_effectors*@Cytoplasm
→
GTP:RHOA:RhoA_cytoskeletal_effectors*@Cytoplasm
- GTP:RHOA:RhoA_cytoskeletal_effectors*@Cytoplasm
→
Actin polymerization@Nucleus
- GTP:RHOB:RhoB_cytoskeletal_effectors*@Cytoplasm
→
Actin polymerization@Nucleus
- RhoA_B*@Cytoplasm
→
GTP:RHOA@Cytoplasm
- RhoA_B*@Cytoplasm
→
GTP:RHOB@Cytoplasm
- GDP:RAC1@Cytoplasm
→
GTP:RAC1@Cytoplasm
- GTP:RAC1@Cytoplasm
→
GDP:RAC1@Cytoplasm
- GTP:RAC1@Cytoplasm
→
ARHGEF14*@Cytoplasm
- GTP:RHOB@Cytoplasm
+ RhoB_cytoskeletal_effectors*@Cytoplasm
→
GTP:RHOB:RhoB_cytoskeletal_effectors*@Cytoplasm
- GTP:RAC1@Cytoplasm
→
NCKAP1@Cytoplasm
- GTP:RAC1@Cytoplasm
→
CYFIP2@Cytoplasm
- GTP:RAC1@Cytoplasm
+ NCK1@Cytoplasm
→
NCK1:RAC1@Cytoplasm
- CDC42:GDP@Cytoplasm
→
CDC42:GTP@Cytoplasm
- CDC42:GTP@Cytoplasm
→
CDC42:GDP@Cytoplasm
- PAR6*@Cytoplasm
+ CDC42:GTP@Cytoplasm
→
CDC42:GTP:PAR6*@Cytoplasm
- CDC42:GTP@Cytoplasm
+ CDC42EP*@Cytoplasm
→
CDC42:CDC42EP*@Cytoplasm
- GTP:HRAS@Cytoplasm
→
GDP:HRAS@Cytoplasm
- GTP:RAC1@Cytoplasm
→
Membrane spreading@Cytoplasm
- HH Ligand:PTCH*@Cytoplasm
+ G_alpha__sub_i_endsub_*:G_beta__sub_i_endsub_*:G_gamma__sub_i_endsub_*:SMO@Cytoplasm
+ GTP@Cytoplasm
→
G_alpha__sub_i_endsub_*:G_beta__sub_i_endsub_*:G_gamma__sub_i_endsub_*:HH Ligand:PTCH*:SMO@Cytoplasm
+ GDP@Cytoplasm
- GDP:RAC1@Cytoplasm
+ GTP@Cytoplasm
→
GTP:RAC1@Cytoplasm
+ GDP@Cytoplasm
- GTP:RAC1@Cytoplasm
→
EMT@Cytoplasm
- G_alpha__sub_i_endsub_*:HH Ligand:PTCH*:SMO@Cytoplasm
+ GTP@Cytoplasm
→
G_alpha__sub_i_endsub_*:Ligand:PTCH*:SMO@Cytoplasm
+ GDP@Cytoplasm
- WNT*@default
+ CK1_epsilon_*:E-Cadherin*:LRP5_6*:p120*@Vaceolae
+ s_s_wca1_s211 + GTP@Vaceolae
+ PRR*@Cytoplasm
→
CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ GDP@Vaceolae
- DVL*|pho|S139_emp|S142_emp:_beta_-Arrestin2*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_o*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:p120*@Vaceolae
+ AMER1*:CK1_gamma_*:PtdIns(4,5)-P2@Cytoplasm
→
AMER1*:CK1_epsilon_*:CK1_gamma_*:DVL*|pho|S139_pho|S142_pho:E-Cadherin*:FZD*:G_beta_*:G_gamma_*:LRP5_6*:PRR*:WNT*:_beta_-Arrestin2*:p120*@Vaceolae
+ s_s_wca1_s1187 + G_beta_*:G_gamma_*@Cytoplasm
- PTH@default
+ PTHR*@Cytoplasm
+ GTP@Cytoplasm
+ G_alpha__sub_s_endsub_*:LRP6@Cytoplasm
→
G_alpha__sub_s_endsub_*:LRP6:PTH@Cytoplasm
+ GDP@Cytoplasm
- LRP6|S1544_pho|T1548_pho@Cytoplasm
+ s_s_wnc1_s172 + GTP@Cytoplasm
→
G_alpha__sub_s_endsub_*:LRP6|S1544_pho|T1548_pho@Cytoplasm
+ GDP@Cytoplasm
+ LRP6|S1544_pho|T1548_pho@Cytoplasm
- WNT*@default
+ FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ GTP@Cytoplasm
→
s_s_wnc1_s240 + GDP@Cytoplasm
- GTP:RAC1@Cytoplasm
+ PLC-_beta_*@Cytoplasm
→
s_s_wnc1_s288
- ROR2@Cytoplasm
+ FZD*:GDP:G_alpha_*:G_beta_*:G_gamma_*@Cytoplasm
+ WNT*@default
+ GTP@Cytoplasm
+ CK1_epsilon_*@Cytoplasm
+ CTHRC1@Cytoplasm
+ SYN4*@Cytoplasm
+ PRICKLE1|pho:VANGL*@Cytoplasm
+ PRR*@Cytoplasm
→
CK1_epsilon_*:CTHRC1:PRICKLE1|pho:PRR*:ROR2:SYN4*:VANGL*@Cytoplasm
+ GDP@Cytoplasm
- G_alpha__sub_13q_endsub_*:PAR1_sub_TRUNC_endsub_*@Cytoplasm
+ GTP@Cytoplasm
+ _beta_-Arrestin*@Cytoplasm
→
G_alpha__sub_13q_endsub_*:PAR1_sub_TRUNC_endsub_*:_beta_-Arrestin*@Cytoplasm
+ GDP@Cytoplasm
As Catalyser:
- (PI3KC1-catalytic*:PI3KC1-regulator*)|active@Cytoplasm
→
(PI3KC1-catalytic*:PI3KC1-regulator*)|active@Cytoplasm
- PI(4,5)P2@Cytoplasm
→
I(1,4,5)P3@Cytoplasm
+ DAG@Cytoplasm
- LEF1_TCF3_4*@Nucleus
+ _beta_-Catenin*@Cytoplasm
→
LEF1_TCF3_4*:_beta_-Catenin*@Nucleus
- PAK*@Cytoplasm
→
PAK*|pho|active@Cytoplasm
- MAP3K7_10_11*@Cytoplasm
→
MAP3K7_10_11*@Cytoplasm
- PAR6*@Cytoplasm
→
PAR6*@Cytoplasm
- ARFIP2@Cytoplasm
→
ARFIP2@Cytoplasm
- PIP5K1*@Cytoplasm
→
PIP5K1*@Cytoplasm
- BAIAP2@Cytoplasm
→
BAIAP2@Cytoplasm
- TIAM1@Cytoplasm
→
TIAM1@Cytoplasm
- PAK1@Cytoplasm
→
PAK1@Cytoplasm
- PAK2@Cytoplasm
→
PAK2@Cytoplasm
- PAK3@Cytoplasm
→
PAK3@Cytoplasm
- PAK4@Cytoplasm
→
PAK4@Cytoplasm
- CDC42BPA@Cytoplasm
→
CDC42BPA@Cytoplasm
- WASP_NWASP*@Cytoplasm
→
WASP_NWASP*@Cytoplasm
- MAP3K11@Cytoplasm
→
MAP3K11@Cytoplasm
- PAK1@Cytoplasm
+ NISCH@Nucleus
→
NISCH:PAK1@Cytoplasm
- DVL*@Cytoplasm
+ s_s_wca1_s725 →
DVL*:KLHL*@Cytoplasm
- s_s_wca1_s758 →
JBN*:_beta_-Catenin*@Cilium
- JBN*:_beta_-Catenin*@Cilium
→
s_s_wca1_s764
- ATP6V0C_D*@Vaceolae
→
ATP6V0C_D*@Vaceolae