GRB2:RAF1:RAS*:RTK*:SOS*

Complex GRB2:RAF1:RAS*:RTK*:SOS* map


Complex composition:

  1. RAF1 map
  2. GRB2 map
  3. SOS* map
  4. RTK* map
  5. RAS* map




GRB2:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane

Identifiers
NAME:GRB2:RAF1:RAS*:RTK*:SOS*

References
s_mpk1_re102( Survival  map ):
When Ras assumes an active conformation through binding of GTP a subpopulation of the Raf-1 (C-Raf) protein molecules in cells translocates from the cytosol to the plasma membrane via interaction with P21ras (not modelled).
PMID:8929532
s_mpk1_re103( Survival  map ):
BCL2 protein can target Raf-1 (C-Raf) to mitochondria.
s_s_mpk1_re103( Survival  map ):

Confidence
REF=1 FUNC=4


Modifications:
Participates in complexes:
In compartment: Plasma Membrane
  1. GRB2:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map

Participates in reactions:
As Reactant or Product:

  1. RAF1@Cytoplasm map + GRB2:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map map GRB2:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map

  2. GRB2:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map map GRB2:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map + RAF1|​pho@Mitochondria map

As Catalyser:

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