GPI

Protein GPI map

Identifiers
glucose-6-phosphate isomerase
HUGO:GPI HGNC:4458 ENTREZ:2821 UNIPROT:P06744 GENECARDS:GPI REACTOME:55226 KEGG:2821 ATLASONC:GC_GPI WIKI:GPI

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Apoptosis  map  / MITOCH_METABOLISM  map

GPI|​hm2@Cytoplasm

References
a_re248( Apoptosis  map ):
PMID:15637053
in human fibrosarcoma HT1080 cells, phosphorylation of GPI by CK2 decreases its enzymatic activity and (non-phosphorylatable or phospho-mimetic mutants)
in HT1080, knock-down of CK2 promotes GPI activity
in vitro, in HT1080 cells, phosphomimetic GPI mutant forms tetramers
in vitro, CK2 triggers GPI tetramerisation
PMID:11004567
in vitro CK2 mediated phosphorylation of GPI on S185
in HT1080 cells, Ser phosphorylation of GPI

GPI|​S185_pho|​hm4@Cytoplasm

References
a_re248( Apoptosis  map ):
PMID:15637053
in human fibrosarcoma HT1080 cells, phosphorylation of GPI by CK2 decreases its enzymatic activity and (non-phosphorylatable or phospho-mimetic mutants)
in HT1080, knock-down of CK2 promotes GPI activity
in vitro, in HT1080 cells, phosphomimetic GPI mutant forms tetramers
in vitro, CK2 triggers GPI tetramerisation
PMID:11004567
in vitro CK2 mediated phosphorylation of GPI on S185
in HT1080 cells, Ser phosphorylation of GPI


Modifications:
In compartment: Cytoplasm
  1. GPI@Cytoplasm map

  2. GPI|​hm2@Cytoplasm map
  3. GPI|​S185_pho|​hm4@Cytoplasm map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. rGPI@Nucleus map map GPI@Cytoplasm map

    2. GPI|​hm2@Cytoplasm map map GPI|​S185_pho|​hm4@Cytoplasm map
    3. GPI@Cytoplasm map map GPI|​hm2@Cytoplasm map

    As Catalyser:

    1. glucose-6P@Cytoplasm map map fructose-6P@Cytoplasm map

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