GCK

Protein GCK map

Identifiers
glucokinase (hexokinase 4)
HUGO:GCK HGNC:4195 ENTREZ:2645 UNIPROT:P35557 GENECARDS:GCK REACTOME:403830 KEGG:2645 ATLASONC:GC_GCK WIKI:GCK

Maps_Modules
 Apoptosis  map  / MITOCH_METABOLISM  map
 Apoptosis  map  / MOMP_REGULATION  map

GCK@Cytoplasm

References
a_re245( Apoptosis  map ):
PMID:10531306
allosterinc inhibition of HK1 by glucose 6P
PMID:11078441
HK inhibition by long-chain acyl-CoAs
PMID:10760476
PMID:7130182
GCK inhibition by long-chain acyl-CoAs
PMID:12931191
in mouse liver mitochondria GCK activation by phosphorylated BAD within a mitochondrial protein complex
a_re641( Apoptosis  map ):
in mouse liver mitochondria, protein complex purification


Modifications:
In compartment: Cytoplasm
  1. GCK@Cytoplasm map

Participates in complexes:
In compartment: Mitochondrial outer membrane

  1. BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map

  2. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map

Participates in reactions:
As Reactant or Product:

  1. BAD|​S91_unk|​active@Cytoplasm map + GCK@Cytoplasm map + WASF1@Cytoplasm map + PRKAC*@Cytoplasm map + PPP1C*@Cytoplasm map map BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map

  2. BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map map BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map
  3. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map map BAD|​S91_unk:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial outer membrane map

As Catalyser:

  1. glucose@Cytoplasm map + ATP@Cytoplasm map map glucose-6P@Cytoplasm map + ADP@Cytoplasm map

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