GADD45*

RNA GADD45* map

Identifiers
Growth arrest and DNA-damage-inducible, alpha
HUGO:GADD45A HGNC:4095 ENTREZ:1647 UNIPROT:P24522 GENECARDS:GADD45A KEGG:1647 ATLASONC:GC_GADD45A WIKI:GADD45A
growth arrest and DNA-damage-inducible beta
HUGO:GADD45B HGNC:4096 ENTREZ:4616 UNIPROT:O75293 GENECARDS:GADD45B KEGG:4616 ATLASONC:GC_GADD45B WIKI:GADD45B
growth arrest and DNA-damage-inducible gamma
HUGO:GADD45G HGNC:4097 ENTREZ:10912 UNIPROT:O95257 GENECARDS:GADD45G KEGG:10912 ATLASONC:GC_GADD45G WIKI:GADD45G

Maps_Modules
 DNA repair  map  / G2_M_CHECKPOINT  map
 DNA repair  map  / NER  map
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:19004803
CyclinB1/CDC2 (CDK1) complex is inhibited by GADD45 in responce to DNA damage and causes G2/M arrest
PMID:12124778, PMID:19652693, PMID:15917306
PMID:20025601
PMID:20673124

rGADD45*@default

References
d_re226( DNA repair  map ):
BRCA1 up-regulates transcription of GADD45 in p53 independed manner:
PMID:10367887, PMID:10962562
PMID:19004803, PMID:12496474
p53 enhances transcription of GADD45:
PMID:9892649, PMID:10779360
p53 regulated global genomic NER at the level of DNA damage recognition involving GADD45, XPC, DDB2:
PMID:12771027, PMID:9346961

rGADD45*@Nucleus

References
s_akt2_re79( Survival  map ):
PMID:17646672
PMID20673124


Modifications:
In compartment: Nucleus
  1. rGADD45*@Nucleus map

In compartment: default

  1. rGADD45*@default map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. gGADD45*@default map map rGADD45*@default map

    2. rGADD45*@default map map GADD45A@default map
    3. gGADD45*@Nucleus map map rGADD45*@Nucleus map

    As Catalyser:

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