GAB1:GF:GRB2:PI3,4,5-P3:RAS*:RTK*:SOS*:p110*:p85*

Complex GAB1:GF:GRB2:PI3,4,5-P3:RAS*:RTK*:SOS*:p110*:p85* map


Complex composition:

  1. GF map
  2. PI3,4,5-P3 map
  3. GRB2 map
  4. p85* map
  5. p110* map
  6. SOS* map
  7. RAS* map
  8. RTK* map
  9. GAB1 map




GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome

Identifiers
NAME:GAB1:GF:GRB2:PI3,4,5-P3:RAS*:RTK*:SOS*:p110*:p85*

References
s_akt1_re136( Survival  map ):
PMID:10514377
PMID:17635922

Confidence
REF=2 FUNC=4

GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft

Identifiers
NAME:GAB1:GF:GRB2:PI3,4,5-P3:RAS*:RTK*:SOS*:p110*:p85*

References
s_akt1_re11( Survival  map ):
PMID:15584861
PMID:10648629
s_akt1_re3( Survival  map ):
PMID:15534002
PMID:9779982
PMID:14585353

Confidence
REF=2 FUNC=4


Modifications:
Participates in complexes:
In compartment: Endosome
  1. GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map

In compartment: Lipid Raft

  1. GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map

Participates in reactions:
As Reactant or Product:

  1. p110*:​p85*@Cytoplasm map + s_s_akt1_s53 + PI3,4,5-P3@Lipid Raft map + RTK*@Cytoplasm map + GF@default map + RAS*@Cytoplasm map + GAB1|​Y977_pho|​Y989_pho@Cytoplasm map map GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map

  2. GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map map Ubiquitination@Cytoplasm map
  3. GAB1|​Y977_pho|​Y989_pho:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Lipid Raft map map GAB1:​GF:​GRB2:​PI3,4,5-P3:​RAS*:​RTK*|​pho|​pho|​hm2:​SOS*:​p110*:​p85*@Endosome map

As Catalyser:

  1. PtdIns(4,5)-P2@Lipid Raft map map PI3,4,5-P3@Lipid Raft map

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