G_alpha__sub_13q_endsub_*:PAR1_sub_TRUNC_endsub_*

Complex G_alpha__sub_13q_endsub_*:PAR1_sub_TRUNC_endsub_* map


Complex composition:

  1. PAR1_sub_TRUNC_endsub_* map
  2. G_alpha__sub_13q_endsub_* map




G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*@Cytoplasm

Identifiers
NAME:G_alpha__sub_13q_endsub_*:PAR1_sub_TRUNC_endsub_*

References
s_wnc1_re7( Survival  map ):
PAR1 is activated by cleavage of exodomain at Arg41-Ser42
PMID:14652070
PAR1 can be activated by MMP1
PMID:15707890
s_wnc1_re1( Survival  map ):
PMID:21506126
PAR1 can induce AKT phosphorylation; exact mechanism unknown also wich residues are unknown
PMID:17374729
s_wnc1_re8:( Survival  map ) PMID:11694535
s_wnc1_re15:( Survival  map ) PMID:20223821
s_wnc1_re21( Survival  map ):
PAR1 silencing leads to increased protein level of activated caspase3 and 9. Increased protein level of Bim, Bax
s_s_wnc1_re21( Survival  map ):

Confidence
REF=5 FUNC=5


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*@Cytoplasm map map Apoptosis@Cytoplasm map

  2. G_alpha__sub_13q_endsub_*:​PAR1*@Cytoplasm map map G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*@Cytoplasm map
  3. G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*@Cytoplasm map + GTP@Cytoplasm map + _beta_-Arrestin*@Cytoplasm map map G_alpha__sub_13q_endsub_*:​PAR1_sub_TRUNC_endsub_*:​_beta_-Arrestin*@Cytoplasm map + GDP@Cytoplasm map

As Catalyser:

  1. AKT1@Cytoplasm map map AKT1|​pho@Cytoplasm map

  2. DVL*@Cytoplasm map map DVL*|​pho|​emp|​emp@Cytoplasm map

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