fumarate

Simple molecule fumarate map
fumarate@Cytoplasm

References
a_re387( Apoptosis  map ):
PMID:12351678
identification of PHD2 as a HIF1A prolyl hydroxylase
PMID:15652751
inhibition of HIF1A prolyl hydroxylation by succinate and fumarate
PMID:15721254
in 293 cells, OS9 interacts with HIF1 and PHD and promotes HIF1A prolylhydroxylation and degradation

fumarate@Mitochondrial Matrix

Identifiers
CHEBI:29806 KEGGCOMPOUND:C00122 CAS:142-42-7

Maps_Modules
 Apoptosis  map  / CASPASES  map
 Apoptosis  map  / MITOCH_METABOLISM  map


Modifications:
In compartment: Cytoplasm
  1. fumarate@Cytoplasm map

In compartment: Mitochondrial Matrix

  1. fumarate@Mitochondrial Matrix map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. succinate@Mitochondrial Matrix map + ubiquinone@Mitochondrial inner membrane map map fumarate@Mitochondrial Matrix map + ubiquinol@Mitochondrial inner membrane map

    2. fumarate@Mitochondrial Matrix map map malate@Mitochondrial Matrix map

    As Catalyser:

    1. HIF1A@Cytoplasm map + O_sub_2_endsub_@Cytoplasm map + 2-oxoglutarate@Cytoplasm map map HIF1A|​P564_hyd@Cytoplasm map + succinate@Cytoplasm map + CO_sub_2_endsub_@Cytoplasm map

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