Fibronectin partners*

Protein Fibronectin partners* map

Identifiers
Fibronectin partners
NAME:a5b1*
ITGA5/ITGB1
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
HUGO:ITGA5 HGNC:6141 ENTREZ:3678 UNIPROT:P08648 GENECARDS:ITGA5 REACTOME:57569 KEGG:3678 ATLASONC:GC_ITGA5 WIKI:ITGA5
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
HUGO:ITGB1 HGNC:6153 ENTREZ:3688 UNIPROT:P05556 GENECARDS:ITGB1 REACTOME:57597 KEGG:3688 ATLASONC:GC_ITGB1 WIKI:ITGB1
NAME:aVb3*
ITGAV/ITGB3
integrin, alpha V
“antigen identified by monoclonal antibody L230″, “integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)”, MSK8, “vitronectin receptor”, VNRA, VTNR
HUGO:ITGAV HGNC:6150 ENTREZ:3685 UNIPROT:P06756 GENECARDS:ITGAV REACTOME:57593 KEGG:3685 ATLASONC:GC_ITGAV WIKI:ITGAV
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
GP3A
HUGO:ITGB3 HGNC:6156 ENTREZ:3690 UNIPROT:P05106 GENECARDS:ITGB3 REACTOME:57601 KEGG:3690 ATLASONC:GC_ITGB3 WIKI:ITGB3
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
GP2B, “integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)”
HUGO:ITGA2B HGNC:6138 ENTREZ:3674 UNIPROT:P08514 GENECARDS:ITGA2B REACTOME:57579 KEGG:3674 ATLASONC:GC_ITGA2B WIKI:ITGA2B
NAME:a2b1*
ITGA2/ITGB1
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
CD49B
HUGO:ITGA2 HGNC:6137 ENTREZ:3673 UNIPROT:P17301 GENECARDS:ITGA2 REACTOME:57563 KEGG:3673 ATLASONC:GC_ITGA2 WIKI:ITGA2
NAME:a10b1*
ITGA10/ITGB1
integrin, alpha 10
HUGO:ITGA10 HGNC:6135 ENTREZ:8515 UNIPROT:O75578 GENECARDS:ITGA10 REACTOME:57585 KEGG:8515 ATLASONC:GC_ITGA10 WIKI:ITGA10

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map
 EMT  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:19487819
During gastrulation, type 1 EMT is associated with de novo expression of a5b1, which is a receptor for fibronectin.
Type 2 EMT in experimental kidney fibrosis is associated with increased a5 integrin expression.


Modifications:
In compartment: Extracellular space
  1. Fibronectin partners*@Extracellular space map

Participates in complexes:
In compartment: Extracellular space

  1. Fibronectin partners*:​Fibronectin*@Extracellular space map

Participates in reactions:
As Reactant or Product:

  1. Fibronectin*@Extracellular space map + Fibronectin partners*@Extracellular space map map Fibronectin partners*:​Fibronectin*@Extracellular space map

  2. Fibronectin partners*:​Fibronectin*@Extracellular space map map Cell-matrix adhesions@Extracellular space map
  3. Fibronectin partners*@Extracellular space map map a5b1*_aVb3*@Extracellular space map
  4. Fibronectin partners*@Extracellular space map map ITGA2B:​ITGB3@Cytoplasm map
  5. Fibronectin partners*@Extracellular space map map ITGA10:​ITGB1@Cytoplasm map
  6. Fibronectin partners*@Extracellular space map map ITGA2:​ITGB1@Cytoplasm map

As Catalyser:

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