FGFR3-ligands*

Protein FGFR3-ligands* map

Identifiers
fibroblast growth factor 1 (acidic)
HUGO:FGF1 HGNC:3665 ENTREZ:2246 UNIPROT:P05230 GENECARDS:FGF1 REACTOME:54762 KEGG:2246 ATLASONC:GC_FGF1 WIKI:FGF1
fibroblast growth factor 2 (basic)
FGFB
HUGO:FGF2 HGNC:3676 ENTREZ:2247 UNIPROT:P09038 GENECARDS:FGF2 REACTOME:54764 KEGG:2247 ATLASONC:FGF2ID511ch4q27 WIKI:FGF2
fibroblast growth factor 8 (androgen-induced)
“fibroblast growth factor 9 (glia-activating factor)”

Maps_Modules
 EMT  map  / EMT_REGULATORS  map
 EMT  map  / ECM  map

References
PMID:14517404
Fibroblast growth factor FGF1, a prototypic member of the FGF family, has the ability to stimulate angiogenesis in an in vivo model of angiogenesis.
Eggs received secreted FGF1 showed a significant increase in vascularization when compared to eggs received vector alone plasmids.
PMID:16272825
This FGF1-mediated angiogenesis involves in the PI3K/AKT pathway.
Blocked PI3K pathway via LY294002 in FGF1-transfected CAMs (chicken chorio- allantoic membrane) signifi cantly inhibited angiogenesis
PMID:16682805
Both activity and mRNA expression levels of the Ets1 molecule were increased in response to FGF1 overexpression
Ets-1 activation is a requisite for FGF1-mediated angiogenesis in vivo.


Modifications:
In compartment: Extracellular space
  1. FGFR3-ligands*@Extracellular space map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. FGFR3-ligands*@Extracellular space map map FGF1@Extracellular space map

    2. FGFR3-ligands*@Extracellular space map map FGF2@Extracellular space map
    3. FGFR3-ligands*@Extracellular space map map FGF8@Extracellular space map
    4. FGFR3-ligands*@Extracellular space map map FGF9@Extracellular space map
    5. FGF family*@Extracellular space map map FGFR3-ligands*@Extracellular space map

    As Catalyser:

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