FANCD2:FANCI:POLN

Complex FANCD2:FANCI:POLN map


Complex composition:

  1. POLN map
  2. FANCD2 map
  3. FANCI map




FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@default

Identifiers
NAME:FANCD2:FANCI:POLN

Maps_Modules
 DNA repair  map  / HR  map
 DNA repair  map  / FANCONI  map

References
PolN:FANCD2:FANCI complex activate HR
PMID:16337602
d_re139( DNA repair  map ):
PMID:19686080
POLH participates in the D-loop formation in HR:
PMID:16337602, PMID:16337601
Complex PolN:HEL308 participates in HR and in Fanconi PMID:19995904
d_re163( DNA repair  map ):
POLH activates D-loop extention
PoLN:HEL308* participate in HR and Fanconi. PolN:FANCD2:FANCI complex activate HR:
Presence of FA core complex is essential for thePolZ/Rev1 activity:
PMID:18448394
PoLQ/HEL308 in Fancon:
PMID:18472307
d_re165( DNA repair  map ):
Link between Fanconi pathway and HR.
Fanconi pathway is a coordination of NER, TLS and HR
PMID:19686080:G
POLH activates D-loop extension. PoLN:HEL308* participate in HR and Fanconi. PolN:FANCD2:FANCI complex activate HR:
For role of SMARCAL1/RPA in stalled replication fork repair and in the homologous recombination:
PMID:19841479, PMID:19793861, PMID:19793862

Confidence
REF=5 FUNC=5


Modifications:
Participates in complexes:
In compartment: default
  1. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@default map

Participates in reactions:
As Reactant or Product:

  1. FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho@default map + POLN@default map map FANCD2|​K561_ubi|​pho:​FANCI|​K523_ubi|​pho:​POLN@default map

As Catalyser:

  1. gHR_DNA_st3*@Nucleus map map gHR_DNA_st4*@Nucleus map

  2. gFanconi_DNA_st4*@Nucleus map map gFanconi_DNA_st5*@Nucleus map
  3. gFanconi_DNA_st4*@Nucleus map map gHR_DNA_st2*@Nucleus map

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