FANCC

Protein FANCC map

Identifiers
Fanconi anemia, complementation group C
HUGO:FANCC HGNC:3584 ENTREZ:2176 UNIPROT:Q00597 GENECARDS:FANCC REACTOME:54634 KEGG:2176 ATLASONC:FACC101 WIKI:FANCC

Maps_Modules
 DNA repair  map  / FANCONI  map
 DNA repair  map  / TLS  map

References
PMID:19686080, PMID:19622404, PMID:18931676
FA core complex regulates REV1 and activated TLS
PMID:22266823

FANCC@default

References
d_re203( DNA repair  map ):
The complex activates HR
PMID:18212739


Modifications:
In compartment: default
  1. FANCC@default map

Participates in complexes:
In compartment: default

  1. FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map

  2. BRCA2:​FANCC:​FANCG|​S7_pho:​XRCC3@default map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

Participates in reactions:
As Reactant or Product:

  1. FANCC@default map + FANCE|​S376_pho|​T346_pho@default map + FANCF@default map map FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map

  2. FANCA|​pho:​FANCG|​S7_pho@default map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map + FAAP24*:​FANCM@default map + FAAP100*:​FANCB:​FANCL@default map + BLM@Nucleus map + HES1@default map + FAAP20*@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map
  4. FANCG|​S7_pho@default map + BRCA2@default map + XRCC3@default map + FANCC@default map map BRCA2:​FANCC:​FANCG|​S7_pho:​XRCC3@default map

As Catalyser:

  1. gHR_DNA_st1*@Nucleus map map gHR_DNA_st2*@Nucleus map

  2. gFanconi_DNA_st2*@Nucleus map map gFanconi_DNA_st3*@Nucleus map
  3. FANCD2|​pho@default map map FANCD2|​K561_ubi|​pho@default map
  4. FANCI|​pho@default map map FANCI|​K523_ubi|​pho@default map
  5. gFanconi_DNA_st4*@Nucleus map map gFanconi_DNA_st5*@Nucleus map
  6. gFanconi_DNA_st4*@Nucleus map map gHR_DNA_st2*@Nucleus map
  7. FANCD2@default map map FANCD2|​pho@default map
  8. FANCD2|​K561_ubi|​pho@default map + MRE11*:​NBS1*|​S343_pho:​RAD50@default map + ATR|​pho|​active@Nucleus map map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@default map
  9. gTLS_DNA_st1*@Nucleus map map gTLS_DNA_st2*@Nucleus map

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