FAAP24*

Protein FAAP24* map

Identifiers
chromosome 19 open reading frame 40, “Fanconi anemia-associated protein, 24 kDa”
HUGO:C19orf40 HGNC:28467 ENTREZ:91442 UNIPROT:Q9BTP7 GENECARDS:C19orf40 REACTOME:229329 KEGG:91442 ATLASONC:GC_C19orf40 WIKI:C19orf40

Maps_Modules
 DNA repair  map  / S_PHASE_CHECKPOINT  map
 DNA repair  map  / FANCONI  map
 DNA repair  map  / TLS  map

References
PMID:19686080, PMID:19622404, PMID:18931676
FANCM/FAAP24 is a sensor of ICL and recruiter of Fanconi core complex
PMID:19622404
HCLK2*/FANCM/FAAP24/active ATR complex inhibit S-phase
PMID:19282663, PMID:19622404
FA core complex regulates REV1 and activated TLS
PMID:22266823

FAAP24*@default

References
d_re199( DNA repair  map ):
HCLK2*/FANCM/FAAP24/active ATR complex inhibit S-phase:
PMID:19282663, PMID:19622404, PMID:18995830


Modifications:
In compartment: default
  1. FAAP24*@default map

Participates in complexes:
In compartment: default

  1. FAAP24*:​FANCM@default map

  2. ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@default map
  3. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

Participates in reactions:
As Reactant or Product:

  1. FAAP24*@default map + FANCM@default map map FAAP24*:​FANCM@default map

  2. FANCA|​pho:​FANCG|​S7_pho@default map + FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF@default map + FAAP24*:​FANCM@default map + FAAP100*:​FANCB:​FANCL@default map + BLM@Nucleus map + HES1@default map + FAAP20*@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map
  3. HCLK2*@default map + FAAP24*@default map + FANCM@default map + ATR|​pho|​active@Nucleus map map ATR|​pho:​FAAP24*:​FANCM:​HCLK2*@default map
  4. BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1@default map + TOP3A@default map + RPA1:​RPA2:​RPA3@default map map BLM:​FAAP100*:​FAAP20*:​FAAP24*:​FANCA|​pho:​FANCB:​FANCC:​FANCE|​S376_pho|​T346_pho:​FANCF:​FANCG|​S7_pho:​FANCL:​FANCM:​HES1:​RPA1:​RPA2:​RPA3:​TOP3A@default map

As Catalyser:

  1. S phase@default map map G2 phase@default map

  2. G2 phase@default map map M phase@default map
  3. gFanconi_DNA_st1*@Nucleus map map gFanconi_DNA_st2*@Nucleus map
  4. gFanconi_DNA_st2*@Nucleus map map gFanconi_DNA_st3*@Nucleus map
  5. FANCD2|​pho@default map map FANCD2|​K561_ubi|​pho@default map
  6. FANCI|​pho@default map map FANCI|​K523_ubi|​pho@default map
  7. gFanconi_DNA_st4*@Nucleus map map gFanconi_DNA_st5*@Nucleus map
  8. FANCD2@default map map FANCD2|​pho@default map
  9. FANCD2|​K561_ubi|​pho@default map + MRE11*:​NBS1*|​S343_pho:​RAD50@default map + ATR|​pho|​active@Nucleus map map ATR|​pho:​FANCD2|​K561_ubi|​pho:​MRE11*:​NBS1*|​S343_pho:​RAD50@default map
  10. gTLS_DNA_st1*@Nucleus map map gTLS_DNA_st2*@Nucleus map

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