ERCC1

Protein ERCC1 map

Identifiers
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
HUGO:ERCC1 HGNC:3433 ENTREZ:2067 UNIPROT:P07992 GENECARDS:ERCC1 REACTOME:54428 KEGG:2067 ATLASONC:ERCC1ID40481ch19q13 WIKI:ERCC1

Maps_Modules
 DNA repair  map  / NER  map
 DNA repair  map  / A_NHEJ  map
 DNA repair  map  / FANCONI  map
 DNA repair  map  / SSA  map

References
PMID:22373527, PMID:23085398, PMID:22824526, PMID:22373527, PMID:22257761
PMID:19809470, PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153:G, PMID:11900249
For Fanconi pathway
PMID:19686080
For SSA pathway
PMID:19473888, PMID:12947387, PMID:19596235, PMID:19595721, PMID:19596236
For A_NHEJ (alt_NHEJ or B_NHEJ or MMEJ):
PMID:21376743, PMID:24050180, PMID:22743550


Modifications:
In compartment: default
  1. ERCC1@default map

Participates in complexes:
In compartment: default

  1. ERCC1:​XPF*@default map

  2. ERCC1:​SLX4*:​XPF*@default map
  3. ERCC1:​MLH1:​PMS2:​XPF*@default map
  4. CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map

Participates in reactions:
As Reactant or Product:

  1. ERCC1@default map + XPF*@default map map ERCC1:​XPF*@default map

  2. CDK7:​CyclinH*:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@default map + ERCC1@default map + XPF*@default map + XPG*@default map map CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA1:​RPA2|​pho:​RPA3:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@default map
  3. MLH1:​PMS2@default map + ERCC1:​XPF*@default map map ERCC1:​MLH1:​PMS2:​XPF*@default map
  4. SLX4*@default map + ERCC1:​XPF*@default map map ERCC1:​SLX4*:​XPF*@default map

As Catalyser:

  1. gA_NHEJ_DNA_st3*@Nucleus map map gA_NHEJ_DNA_st4*@Nucleus map

  2. gFanconi_DNA_st3*@Nucleus map map gFanconi_DNA_st4*@Nucleus map
  3. gFanconi_DNA_st5*@Nucleus map map gTC-NER_GG-NER_DNA_st4*@Nucleus map
  4. gSSA_DNA_st4*@Nucleus map map gSSA_DNA_st5*@Nucleus map
  5. gTC-NER_GG-NER_DNA_st3*@Nucleus map map gTC-NER_GG-NER_DNA_st4*@Nucleus map + Modified 24-32 nucleotides fragment@default map

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