ELK1

Protein ELK1 map

Identifiers
ELK1, member of ETS oncogene family
HUGO:ELK1 HGNC:3321 ENTREZ:2002 UNIPROT:P19419 GENECARDS:ELK1 REACTOME:403188 KEGG:23415 ATLASONC:GC_ELK1 WIKI:ELK1

Maps_Modules
 Apoptosis  map  / APOPTOSIS_GENES  map
 Survival  map  / MAPK  map

References
Elk1 is one of the best studied targets of the ERK cascade. Phosphorylation increases the transcriptional activity of Elk1.
PMID:16393692

ELK1@Nucleus

References
a_re141( Apoptosis  map ):
PMID:17554199
by p53
PMID:17656095
PMID:17540599
PMID:17554337
PMID:19696787
in TIG3 TERT/ΔB-RAF:ER, by ELK1 (siRNA ELK1 and MIR34A PCR; ChIP)
in HEK293 by ELK1, gene reporter

ELK1|​pho@Nucleus

References
s_mpk1_re91( Survival  map ):
The rapid and efficient phosphorylation of Elk1 by ERKs is enabled by a direct interaction between the two proteins.
ELK1 is a nuclear P38 target.
ELK1 is a nuclear JNK target.
PMID:16393692 PMID:20506250 PMID:11274345
s_mpk1_re212( Survival  map ):
ELK1 induces c-fos expression.
PMID:11274345


Modifications:
In compartment: Nucleus
  1. ELK1@Nucleus map

  2. ELK1|​pho@Nucleus map

Participates in complexes:

    Participates in reactions:
    As Reactant or Product:

    1. ELK1|​pho@Nucleus map map gFOS@Nucleus map

    2. ELK1@Nucleus map map ELK1|​pho@Nucleus map

    As Catalyser:

    1. gMIR34A@Nucleus map map arMIR34A@Cytoplasm map

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