e_re966

Reaction known_transition_omitted e_re966 map

VAV1@Cytoplasm map VAV1@Cytoplasm map

Reaction regulators:

Catalysis
  1. FYN@Cytoplasm map
Physical_stimulation
  1. Vitronectin*:​aVb3*_aVb5*@Extracellular space map



References
PMID:9822663
FYN is required for VAV1 phosphorylation and thus activation.
PMID:15699036
tyrosine phosphorylation of beta3 integrin and aVb3-mediated adhesion are required for VAV1 assocaition and Rho activation.
Vav1 associates with aVb3 upon cell adhesion to vitronectin

Confidence
REF=2 FUNC=4


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