e_re767

Reaction positive_influence e_re767 map

GTP:​RAC1@Cytoplasm map ARHGEF14*@Cytoplasm map

No reaction regulators

References
PMID:14701795
Activated Rac1 activates ARHGEF14 which is a common activator for CDC2 and RHOA
Co-expression of Dbs with activated Rac1 causes enhanced focus forming activity and elevated levels of GTP-bound RhoA in NIH 3T3 cells, indicating that Dbs is activated by the interaction.

Confidence
REF=1 FUNC=5


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