e_re761

Reaction known_transition_omitted e_re761 map

PAK*@Cytoplasm map PAK*|​pho|​active@Cytoplasm map

Reaction regulators:

Physical_stimulation
  1. GTP:​RAC1@Cytoplasm map



References
PMID:8805275
PMID:8910277
PMID:9744077
PMID:10023776
PMID:11728826
GTP-bound Rac1 activates PAK1,2,3.
The binding of the active GTP form of Rac1 and the PBD domain of PAK1,2,3 promotes autophosphorylation of PAK1,2,3 and activation of JNK pathway.

Confidence
REF=3 FUNC=4


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