e_re24

Reaction transcription e_re24 map

gVEGFA@Nucleus map rVEGFA@Nucleus map

Reaction regulators:

Inhibition
  1. LMO2:​ZEB1@Nucleus map
Physical_stimulation
  1. HIF1B*:​HIF_alpha_*@Nucleus map
  2. TWIST1|​S68_pho@Nucleus map
  3. STAT3|​pho|​active@Nucleus map



References
PMID:13130303
Keratin-14, 18, 19, Vimentin are putative direct HIF1 target genes
http://www.omicsonline.org/1948-5956/JCST-03-035.php
Genes induced by HIF-1 in cancer cells include KRT-14, 18, 19, Vimentin, VEGF
PMID:9278421
HIF1 target genes include TGFB3, VEGF
PMID:7768934
VEGF is induced by hypoxia in a HIF1-dependent way
PMID:11528470
Prokinecticin 1 (EG-VEGF) is induced by hypoxia through a potential HIF1-dependent mechanism indicates that this gene is in the same homeostatic cascade as VEGF, Flt1 and erythropoietinPMID:17987801 PMID:16716598

Confidence
REF=3 FUNC=4


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