e_re1257

Reaction positive_influence e_re1257 map

ROS@Mitochondria map HIF1A@Cytoplasm map

No reaction regulators

References
PMID:10833514
Hypoxia increases mitochondrial ROS generation at Complex III, which causes accumulation of HIF-1alpha protein
Mitochondria-derived ROS are both required and sufficient to initiate HIF-1 alpha stabilization during hypoxia.

Confidence
REF=1 FUNC=0


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