e_re1229

Reaction translation e_re1229 map

rRAC1@Nucleus map RAC1B*@Cytoplasm map

Reaction regulators:

Physical_stimulation
  1. MMP3@Cytoplasm map



References
PMID:21667018
Rac1B is an alternatively spliced form of Rac1 gene.
Rac1B does not lead to lamellipodia formation, or the activation of PAK1, AKT1, or c-Jun-NH2- kinase activities.
However, Rac1B retains the ability to stimulate the NF-kappa-B pathway.
PMID:16001073
MMP3 can induce the expression of RACB1.
RACB1 increases the cellular levels of ROS, causing an upregulation of Snail and induction of EMT.

Confidence
REF=2 FUNC=3


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