E1*:FAF*:NEDD8:RAD6*:SKP*

Complex E1*:FAF*:NEDD8:RAD6*:SKP* map


Complex composition:

  1. SKP* map
  2. RAD6* map
  3. E1* map
  4. NEDD8 map
  5. FAF* map




E1*:​FAF*:​NEDD8:​RAD6*:​SKP*@Cytoplasm

Identifiers
NAME:E1*:FAF*:NEDD8:RAD6*:SKP*

References
s_wca1_re46( Survival  map ):
PMID:15688063 PMID:22730322
FAF1 acts as scaffold protein
s_wca1_re47( Survival  map ):
PMID:19576224 PMID:17143292 PMID:10023660 PMID:21411632 PMID:22730322 PMID:22682247
FAF1 enhances poly-ubiquitination of beta-catenin by acting as scaffold protein
Intact destruction complex in the proteosome complex

Confidence
REF=5 FUNC=3


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. E1*:​FAF*:​NEDD8:​RAD6*:​SKP*@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. E1*@Cytoplasm map + RAD6*@Cytoplasm map + NEDD8@Cytoplasm map + s_s_wca1_s1717 + FAF*@Cytoplasm map map E1*:​FAF*:​NEDD8:​RAD6*:​SKP*@Cytoplasm map

As Catalyser:

  1. AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho@Cytoplasm map + E1*:​FAF*:​NEDD8:​RAD6*:​SKP*@Cytoplasm map + CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​PKD*:​USP15@Cytoplasm map map AMER1*:​APC|​S1505_pho|​S1501_pho|​S1504_pho|​S1507_pho|​S1503_pho|​S1510_pho:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​CK2_beta_*:​CSN1*:​CSN2*:​CSN3*:​CSN4*:​CSN5*:​CSN6*:​CSN7*:​CSN8*:​E1*:​FAF*:​GSK3*:​NEDD8:​PKD*:​PtdIns(4,5)-P2:​RAD6*:​SKP*:​USP15:​_beta_-Catenin*|​S45_pho|​T41_pho|​S37_pho|​S33_pho|​K19_ubi|​K49_ubi@Cytoplasm map

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