DUSP1

Protein DUSP1 map

Identifiers
dual specificity phosphatase 1
HUGO:DUSP1 HGNC:3064 ENTREZ:1843 UNIPROT:P28562 GENECARDS:DUSP1 KEGG:1843 ATLASONC:DUSP1ID40371ch5q35 WIKI:DUSP1
PTPN10

Maps_Modules
 Apoptosis  map  / TNF_RESPONSE  map
 Survival  map  / MAPK  map

References
synonym:MKP-1
MKP-1 (DUSP1) preferentially inactivates JNK and P38.
DUSP1 play its phosphatase role in the nucleus.
PMID:19436832 PMID:17496916

DUSP1@Cytoplasm

References
a_re1395:( Apoptosis  map ) reactionType:is.a

DUSP1|​don@Nucleus

References
s_mpk1_re184( Survival  map ):
TNF-induced ROS cause oxidation and inhibition of DUSP1 and DUSP5.
PMID:15766528

DUSP1@Nucleus

References
s_mpk1_re221:( Survival  map ) Translation
s_mpk1_re180( Survival  map ):
MKP-1 (DUSP1) preferentially inactivates JNK and P38.
PMID:19436832
s_mpk1_re184( Survival  map ):
TNF-induced ROS cause oxidation and inhibition of DUSP1 and DUSP5.
PMID:15766528


Modifications:
In compartment: Cytoplasm
  1. DUSP1@Cytoplasm map

In compartment: Nucleus

  1. DUSP1@Nucleus map

  2. DUSP1|​don@Nucleus map

Participates in complexes:
In compartment: Nucleus

  1. DUSP1:​JNK*@Nucleus map

  2. DUSP1:​p38*@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. DUSP1@Cytoplasm map map DUSP*@Cytoplasm map

  2. DUSP1@Nucleus map + JNK*|​pho|​pho@Nucleus map map DUSP1:​JNK*@Nucleus map
  3. DUSP1@Nucleus map + p38*|​pho|​pho@Nucleus map map DUSP1:​p38*@Nucleus map
  4. DUSP1@Nucleus map map DUSP1|​don@Nucleus map
  5. gDUSP1@Nucleus map map DUSP1@Nucleus map

As Catalyser:

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