DP1*:E2F1:PCAF*

Complex DP1*:E2F1:PCAF* map


Complex composition:

  1. DP1* map
  2. PCAF* map
  3. E2F1 map




DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus

Identifiers
NAME:DP1*:E2F1:PCAF*

Maps_Modules
 Cell cycle  map  / E2F1  map

References
c_re86( Cell cycle  map ):
Phosphorylation of E2F1 leads to the end of transcription stimulation.
PMID:15840440
Phosphorylation of DP-1 induce the diminution of the binding of E2F to the DNA (leading to the end of its activation).
PMID:15133492, PMID:9556498, PMID:15123636
Phosphorylation of both DP-1 and E2F1
PMID:16135794
Phosphorylation of E2F-1, 2, 3a and 3b by cyclin A/CDK2 induce E2F degradation.
PMID:11980909
Phosphorylation of E2F1 on Ser-375 increases its binding affinity for pRb.
PMID:16213134
c_re87:( Cell cycle  map ) PMID:15840440, PMID:15133492

Confidence
REF=4 FUNC=4

DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus

Identifiers
NAME:DP1*:E2F1:PCAF*

Maps_Modules
 Cell cycle  map  / E2F1  map

References
c_re86( Cell cycle  map ):
Phosphorylation of E2F1 leads to the end of transcription stimulation.
PMID:15840440
Phosphorylation of DP-1 induce the diminution of the binding of E2F to the DNA (leading to the end of its activation).
PMID:15133492, PMID:9556498, PMID:15123636
Phosphorylation of both DP-1 and E2F1
PMID:16135794
Phosphorylation of E2F-1, 2, 3a and 3b by cyclin A/CDK2 induce E2F degradation.
PMID:11980909
Phosphorylation of E2F1 on Ser-375 increases its binding affinity for pRb.
PMID:16213134
c_re621( Cell cycle  map ):
Protein stabilized by phosphorylation.
PMID:15838517, PMID:15140942
c_re622( Cell cycle  map ):
Upon DNA damage, E2F is stabilized by ATM phosphorylation.
14-3-3 tau mediates E2F1 stabilization. 14-3-3 tau interacts with ATM-phosphorylated E2F1 during DNA damage and inhibits E2F1 ubiquitination. 14-3-3 tau is also required for expression and induction of E2F1 apoptotic targets, such as p73, Apaf-1, and caspases, during DNA damage.
PMID:15494392

Confidence
REF=5 FUNC=4


Modifications:
Participates in complexes:
In compartment: Nucleus
  1. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map

  2. DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map

Participates in reactions:
As Reactant or Product:

  1. DP1*:​E2F1|​Lys_ace@Nucleus map + PCAF*@Nucleus map map DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map

  2. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map PCAF*@Nucleus map + DP1*:​E2F1|​Lys_ace|​Ser364_pho@Nucleus map
  3. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map DP1*:​E2F1|​Lys_ace|​Ser31_pho@Nucleus map + PCAF*@Nucleus map
  4. DP1*:​E2F1|​Lys_ace:​PCAF*@Nucleus map map DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map
  5. DP1*|​pho:​E2F1|​pho|​Lys_ace:​PCAF*@Nucleus map map PCAF*@Nucleus map + E2F1|​pho|​Lys_ace@Nucleus map + DP1*|​pho@Nucleus map

As Catalyser:

    Leave a Reply