(d)ATP:APAF1:Cytochrome_C*

Complex (d)ATP:APAF1:Cytochrome_C* map


Complex composition:

  1. APAF1 map
  2. Cytochrome_C* map
  3. (d)ATP map




(d)ATP:​APAF1:​Cytochrome_C*|​ferroheme@Cytoplasm

Identifiers
NAME:APAF1:Cytochrome_C*:d

References
a_re482( Apoptosis  map ):
PMID:17377525
review on apoptosome formation
PMID:11864614
stoechiometry apoptosome
PMID:12522243
inhibition of apoptosome formation by prothymosin-alpha
PMID:15087373
in HT-29 colon adenocarcinoma cells, siRNA against ACHE prevents the APAF1:CYCS interaction and etoposide-induced
PMID:14622304
AFP positive influence on apoptosome assembly
PMID:18439902
CAS PHAPI and HSP70 enhance apoptosome formation and caspase activation
a_re484( Apoptosis  map ):
PMID:15210107
reviews the differerent hypothesis concerning the biochemical events leading to activation of CASP9
PMID:12773388
in vitro, survivin and HBXIP together inhibits CASP9 processing and activation
in HT1080 cells, coexpression of BIRC5 and HBXIP suppresses staurosporin-induced apoptosis
in cell extracts from Hela transfected with siRNA against HBXIP, CYCS induced caspase activation is suppressed
PMID:10329646
by NOD1

Confidence
REF=5 FUNC=5


Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. (d)ATP:​APAF1:​Cytochrome_C*|​ferroheme@Cytoplasm map

Participates in reactions:
As Reactant or Product:

  1. Cytochrome_C*|​ferroheme@Cytoplasm map + (d)ATP@Cytoplasm map + APAF1@Cytoplasm map map (d)ATP:​APAF1:​Cytochrome_C*|​ferroheme@Cytoplasm map

As Catalyser:

  1. Caspase9*@Cytoplasm map map cleaved~Caspase9*@Cytoplasm map

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